Advanced Blood-Brain Barrier Drug Delivery

Advanced Blood-Brain Barrier Drug Delivery

Advanced Blood-Brain Barrier Drug Delivery is a reprint with a summary editorial, followed by 16 chapters that cover five areas of brain drug delivery, including receptor-mediated transport (RMT), carrier-mediated transport (CMT), active efflux transport (AET), Trojan horse lipid nanoparticles (LNP)...

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Bibliographic Details
Format: eBook
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
Subjects:
Medicine and Nursing
Pharmacology
6-OHDA
agonist antibody
alpha-synuclein (αSYN)
Alzheimer's disease
amyotrophic lateral sclerosis (ALS)
antibody
ATP-binding cassette transporters
BBB-peptide shuttle
bispecific antibody
blood-brain barrier
blood-brain barrier (BBB)
brain delivery
brain drug delivery
carrier-mediated transport
cavernous sinus
cell toxicity
chaperonin-containing TCP-1
choline transporter-like protein-1 (CTL1)
compartmental models
decoy receptors
drug delivery
endosomal
endothelium
enzyme replacement therapy
fusion proteins
genetic engineering
hCMEC/D3 cells
IGF1R
IgG fusion proteins
immunotherapy
insulin receptor
ischemic stroke
large amino acid transporter 1 (LAT1)
lipid nanoparticle
liposome
liposomes
lysosomal storage disease
lysosomal storage disorders
molecular Trojan horse
monocarboxylate transporters (MCTs)
monoclonal antibody
mRNA transfection
n/a
nanoparticle
nanoparticles
neurodegeneration
neuronopathic mucopolysaccharidosis
neuroprotection
neurotensin
neurotrophic factors
NSC-34 cell lines
organic cation transporters (OCTNs)
Parkinson's disease
Parkinson's disease (PD)
pharmacokinetics
photo-affinity labeling
physiologically based PK models
prodrugs
protein-based therapy
proteomics
proton-coupled organic cation antiporter
receptor-mediated transcytosis
receptor-mediated transcytosis (RMT)
receptor-mediated transport
single domains antibody
SLC transporters
solute carrier (SLC) transporters
solute carriers (SLCs)
ssPalm
SWATH-MS
SWATH-MS (sequential window acquisition of all theoretical-mass spectra)
targeting
taurine transporter (Taut)
TNF-α inhibitor
transferrin
transferrin receptor
transferrin receptor (TfR)
transferrin receptor 1 (TfR1)
translation
TrkB
variable new antigen receptor (VNAR)
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