Advance in the Treatment of Pediatric Leukemia

Advance in the Treatment of Pediatric Leukemia

The book gives an overview on the progress that has been made in the treatment of acute lymphoblastic leukemia (ALL), of acute and chronic myeloid leukemia (AML, CML) and of juvenile myelomonocytic leukemia (JMML). Leukemia is the most common malignant disease in children, and 80% of patients are di...

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Bibliographic Details
Format: eBook
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
Subjects:
Chemistry
Research & information: general
5-azacitidine
ABCC4
acute lymphoblastic leukemia
acute myeloid leukemia
acute pancreatitis
ADC
advances
ALL
allogeneic stem cell transplantation
alternative donors
AML
antibody
antibody-drug conjugate
B-ALL
BCL11B
BCP-ALL
bispecific T-cell engager (BiTE)
CD19
CFTR
childhood acute lymphoblastic leukemia
children
chronic myeloid leukemia
CML
conditioning regimen
COVID-19
diagnosis
DUX4
evolution of CAR T cells
Fc-engineering
FDA-approved CAR products
future directions of CAR T cell therapy
genome
hematopoietic stem cell transplantation
IKZF1
immunizations
immunotherapy
juvenile myelomonocytic leukemia
L-asparaginase
leukemia
limitations and complications of CAR T cell therapy
low-risk ALL
lymphoblastic leukemia
minimal residual disease
myelodysplastic/myeloproliferative disorders
n/a
NOTCH1
NUTM1
other extramedullary relapse
PAX5
pediatric
pediatric leukemia
Ph-like
polymorphism
prognosis
RAS signaling
risk-stratified treatment
SNV
T-ALL
targeted therapy
TcR versus CAR
TRAIL
transcriptome
treatment
treatment related toxicity
tyrosine kinase inhibitor
xenograft
ZNF384
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