Drug Metabolism/Transport and Pharmacokinetics

Drug Metabolism/Transport and Pharmacokinetics

This book serves to highlight the pharmacokinetics/drug-drug interactions and mechanistic understanding in relation to the drug-metabolizing enzymes and drug transporters.This book presents a series of drug metabolism and transport mechanisms that govern the pharmacokinetic features of therapeutic d...

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Bibliographic Details
Format: eBook
Language:English
Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Subjects:
Manufacturing industries
Medicine and Nursing
acute renal failure
anti-obesity agent
automatization
BCRP
biliary excretion
breast cancer resistance protein
Caco-2
carboxylesterase
Carthamus tinctorius extract
catalposide
celecoxib
cisplatin
comparative pharmacokinetic study
compatibility mechanism
compound K
creatinine clearance
CYP3A4
cytochrome P450
cytochrome P450 enzymes
diabetes
dose-dependent pharmacokinetics
drug absorption
drug dosing
drug interaction
drug transporter
drug-drug interaction
DWP16001
efflux transporter
EpiIntestinal
first-pass
fluorescence
food-drug interactions
gentamicin
head-and-neck cancer
healthy Korean subjects
hepatic and intestinal first-pass effect
hepatic CYP3A1(23)
HPLC
HSG4112
human hepatocytes
in vitro human metabolism
influx transporter
inhibition mode
inhibitor
intestinal metabolism
kidney distribution
kinetic analysis
large volume direct injection
mertansine
metabolism
metformin
modeling
nonrenal clearance
notoginseng total saponins
oral availability
organic cation transporter 2
P-gp
pharmacokinetics
physiologically based pharmacokinetic model
population pharmacokinetic
prazosin
protopanaxadiol (PPD)
quercetin
rats
real-time measurements
renal clearance
renal excretion
repaglinide
sodium-glucose cotransporter 2 (SGLT2) inhibitors
stereoselectivity
sulfasalazine
sulfotransferase
taxanes
tiropramide
tissue engineering
tofacitinib
transporter-enzyme interplay
UDP-glucuronosyltransferase
UDP-glucuronosyltransferases
UHPLC-MS/MS
verapamil
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