PI3K signalling

PI3K signalling

The PI3Ks control many key functions in immune cells. PI3Ks phosphorylate PtdIns(4,5)P2 to yield PtdIns(3,4,5)P3. Initially, PI3K inhibitors such as Wortmannin, LY294002 and Rapamycin were used to establish a central role for Pi3K pathway in immune cells. Considerable progress in understanding the r...

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Bibliographic Details
Format:	eBook
Language:	English
Published:	Frontiers Media SA 2015
Series:	Frontiers Research Topics
Subjects:	Medicine and Nursing B cell PI3K pathway inhibitors PI3K/AKT/mTOR Signal Transduction T cell
Online Access:	Open Access: DOAB, download the publication Open Access: DOAB: description of the publication

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