PI3K signalling
The PI3Ks control many key functions in immune cells. PI3Ks phosphorylate PtdIns(4,5)P2 to yield PtdIns(3,4,5)P3. Initially, PI3K inhibitors such as Wortmannin, LY294002 and Rapamycin were used to establish a central role for Pi3K pathway in immune cells. Considerable progress in understanding the r...
| Format: | eBook |
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| Language: | English |
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Frontiers Media SA
2015
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| Series: | Frontiers Research Topics
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| Subjects: | |
| Online Access: | Open Access: DOAB, download the publication Open Access: DOAB: description of the publication |