Molecular mechanisms regulating cytotoxic lymphocyte development and function, and their associations to human diseases

Cytotoxic lymphocytes, comprised of NK cells and cytotoxic T cells, play a pivotal role in immune defense. By directed release of perforin-containing lytic granules, NK and cytotoxic T cells can eradicate pathogen-infected, tumorigenic, and otherwise stressed cells. By the virtue of cytokine and che...

Full description

Bibliographic Details
Format: eBook
Language:English
Published: Frontiers Media SA 2015
Series:Frontiers Research Topics
Subjects:
Online Access:Open Access: DOAB, download the publication
Open Access: DOAB: description of the publication