Genetic and Epigenetic Regulations of Tumor Progression and Metastasis

Genetic and Epigenetic Regulations of Tumor Progression and Metastasis

Genetic aberrations and epigenetic modifications are critical drivers of cancer progression and metastasis. Although recurrent mutations in primary and metastatic cancers have been shown to be concordant, there are several metastasis-associated mutations responsible for resistance to specific therap...

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Bibliographic Details
Format: eBook
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
Subjects:
Medicine and Nursing
Oncology
5-azacytidine
adaptive responses
adipose tissue
angiogenesis
autophagy
brain metastasis
breast cancer
cancer proliferation
cancer therapy
CDH1 gene
CDKN2A
cell adhesion
colorectal cancer
CYSLTR1
CYSLTR2
diagnostic biomarker
DNA methylation
E-cadherin
EMT
EMT genes
endothelial cells
engineered exosomes
epithelial-to-mesenchymal transition
epithelial-to-mesenchymal transition (EMT)
gene transcription
hepatocellular carcinoma
HTR2B
hypoxia
inflammation
intra-tumor heterogeneity
invasive ductal breast cancer
lung adenocarcinoma
lung cancer
metastasis
metastatic cascade
methylation
miRNA and mRNA expression
mutational profile
n/a
omics data analysis
p16
partial-EMT (p-EMT)
PDAC
pericytes
prognosis
promoter
prostate cancer
STAT proteins
tumor microenvironment
tumor mutational burden
uveal melanoma
waterpipe smoke
Zeb1
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Internet

Open Access: DOAB: description of the publication
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