Long-term drug administration in the adult zebrafish using oral gavage for cancer preclinical studies

by Henderson, Rachel E., Garraway, Levi A., Zon, Leonard I., Dang, Michelle
Published 2016

PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury

by North, Trista E., Vedder, Lea M., Lord, Allegra M., Wishnok, John S., Tannenbaum, Steven Robert, Zon, Leonard I., Goessling, Wolfram, Badu, I. Ramesh
Published 2011

A Cdx4-Sall4 Regulatory Module Controls the Transition from Mesoderm Formation to Embryonic Hematopoiesis

by Paik, Elizabeth J, Mahony, Shaun, White, Richard M, Price, Emily N, DiBiase, Anthony, Dorjsuren, Bilguujin, Mosimann, Christian, Davidson, Alan J, Zon, Leonard I, Gifford, David K.
Published 2014

Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway

by Xu, Cong, Fan, Zi Peng, Fogley, Rachel, DiBiase, Anthony, Trompouki, Eirini, Unternaehrer, Juli, Xiong, Fengzhu, Torregroza, Ingrid, Evans, Todd, Megason, Sean G, Daley, George Q., Schier, Alexander F, Young, Richard A, Zon, Leonard I, Muller, Patrick, Young, Richard A.
Published 2014

Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells

by Zhang, Bing, Ma, Sai, Rachmin, Inbal, He, Megan, Baral, Pankaj, Choi, Sekyu, Gonçalves, William A., Shwartz, Yulia, Fast, Eva M., Su, Yiqun, Zon, Leonard I., Regev, Aviv, Buenrostro, Jason D., Cunha, Thiago M., Chiu, Isaac M., Fisher, David E., Hsu, Ya-Chieh
Published 2020

Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human ...

by Chaturantabut, Saireudee, Shwartz, Arkadi, Evason, Kimberley J., Cox, Andrew G., Labella, Kyle, Schepers, Arnout, Yang, Song, Acuña, Mariana, Houvras, Yariv, Mancio Silva, Liliana, Romano, Shannon, Gorelick, Daniel A., Cohen, David E., Zon, Leonard I., Bhatia, Sangeeta N., North, Trista E., Goessling, Wolfram, Bhatia, Sangeeta N
Published 2020

Direct Recruitment of Polycomb Repressive Complex 1 to Chromatin by Core Binding Transcription Factors

by Yu, Ming, Mazor, Tali, Huang, Hui, Huang, Hsuan-Ting, Kathrein, Katie L, Woo, Andrew J, Chouinard, Candace R., Labadorf, Adam, Akie, Thomas E, Moran, Tyler B., Xie, Huafeng, Zacharek, Sima, Taniuchi, Ichiro, Roeder, Robert G, Kim, Carla F., Zon, Leonard I, Fraenkel, Ernest, Cantor, Alan B.
Published 2014

DHODH modulates transcriptional elongation in the neural crest and melanoma

by White, Richard Mark, Cech, Jennifer N., Ratanasirintrawoot, Sutheera, Lin, Charles Y., Rahl, Peter B., Burke, Christopher J., Langdon, Erin, Tomlinson, Matthew L., Mosher, Jack, Kaufman, Charles, Chen, Frank, Long, Hannah K., Kramer, Martin, Datta, Sumon, Neuberg, Donna S., Granter, Scott, Young, Richard A., Morrison, Sean, Wheeler, Grant N., Zon, Leonard I.
Published 2014

Lineage Regulators Direct BMP and Wnt Pathways to Cell-Specific Programs during Differentiation and Regeneration

by Trompouki, Eirini, Bowman, Teresa V, Lawton, Lee N., Fan, Zi Peng, Wu, Dai-Chen, DiBiase, Anthony, Martin, Corey S, Cech, Jennifer N., Sessa, Anna K, Leblanc, Jocelyn L, Li, Pulin, Durand, Ellen M, Mosimann, Christian, Heffner, Garrett C, Daley, George Q., Paulson, Robert F, Young, Richard A, Zon, Leonard I
Published 2014

The SETDB1 histone methyltransferase is recurrently amplified in and accelerates melanoma

by Ceol, Craig J., Houvras, Yariv, Jane-Valbuena, Judit, Bilodeau, Steve, Orlando, David A., Battisti, Valentine, Fritsch, Lauriane, Lin, William M., Hollmann, Travis J., Ferre, Fabrizio, Bourque, Caitlin, Burke, Christopher J., Turner, Laura, Uong, Audrey, Johnson, Laura A., Beroukhim, Rameen, Mermel, Craig H., Loda, Massimo, Ait-, Garraway, Levi A., Young, Richard A., Zon, Leonard I.
Published 2012

Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors

by Doulatov, Sergei, Vo, Linda T., Macari, Elizabeth R., Wahlster, Lara, Kinney, Melissa A., Taylor, Alison M., Barragan, Jessica, Gupta, Manav, McGrath, Katherine, Humphries, Jessica M., DeVine, Alex, Narla, Anupama, Alter, Blanche P., Beggs, Alan H., Agarwal, Suneet, Ebert, Benjamin L., Gazda, Hanna T., Sieff, Colin A., Schlaeger, Thorsten M., Zon, Leonard I., Daley, George Q., Lee, Hsiang-Ying, Lodish, Harvey F
Published 2018

JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia

by Mansour, Marc R., He, Shuning, Li, Zhaodong, Lobbardi, Riadh, Abraham, Brian J., Hug, Clemens, Rahman, Sunniyat, Leon, Theresa E., Kuang, You-Yi, Zimmerman, Mark W., Blonquist, Traci, Gjini, Evisa, Gutierrez, Alejandro, Tang, Qin, Garcia-Perez, Laura, Pike-Overzet, Karin, Anders, Lars, Berezovskaya, Alla, Zhou, Yi, Zon, Leonard I., Neuberg, Donna, Fielding, Adele K., Staal, Frank J.T, Langenau, David M., Sanda, Takaomi, Look, A. Thomas, Young, Richard A.
Published 2018

Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma

by Tan, Justin L., Fogley, Rachel D., Flynn, Ryan A., Ablain, Julien, Yang, Song, Do, Brian T., Laga, Alvaro C., Fujinaga, Koh, Santoriello, Cristina, Greer, Celeste B., Kim, Yoon Jung, Clohessy, John G., Bothmer, Anne, Pandell, Nicole, Avagyan, Serine, Brogie, John E., van Rooijen, Ellen, Hagedorn, Elliott J., Shyh-Chang, Ng, White, Richard M., Price, David H., Pandolfi, Pier Paolo, Peterlin, B. Matija, Zhou, Yi, Kim, Tae Hoon, Asara, John M., Chang, Howard Y., Zon, Leonard I., Saint-André, Violaine, Fan, Zi Peng, Young, Richard A.
Published 2018