Getting to grips with hepatitis

by Zhijian J Chen, Jin Ye
Published 2012-11-01

Sequence specific detection of bacterial 23S ribosomal RNA by TLR13

by Xiao-Dong Li, Zhijian J Chen
Published 2012-10-01

Both K63 and K48 ubiquitin linkages signal lysosomal degradation of the LDL receptor

by Li Zhang, Ming Xu, Elena Scotti, Zhijian J. Chen, Peter Tontonoz
Published 2013-05-01

BHLHE40, a third transcription factor required for insulin induction of SREBP-1c mRNA in rodent liver

by Jing Tian, Jiaxi Wu, Xiang Chen, Tong Guo, Zhijian J Chen, Joseph L Goldstein, Michael S Brown
Published 2018-06-01

MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades

by Siqi Liu, Jueqi Chen, Xin Cai, Jiaxi Wu, Xiang Chen, You-Tong Wu, Lijun Sun, Zhijian J Chen
Published 2013-08-01

IKK∊-Mediated Tumorigenesis Requires K63-Linked Polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 Ubiquitin Ligase Complex

by Alicia Y. Zhou, Rhine R. Shen, Eejung Kim, Ying J. Lock, Ming Xu, Zhijian J. Chen, William C. Hahn
Published 2013-03-01

The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop

by Xu Zhang, Jiaxi Wu, Fenghe Du, Hui Xu, Lijun Sun, Zhe Chen, Chad A. Brautigam, Xuewu Zhang, Zhijian J. Chen
Published 2014-02-01

Murine gamma-herpesvirus 68 hijacks MAVS and IKKbeta to initiate lytic replication.

by Xiaonan Dong, Hao Feng, Qinmiao Sun, Haiyan Li, Ting-Ting Wu, Ren Sun, Scott A Tibbetts, Zhijian J Chen, Pinghui Feng
Published 2010-07-01

HSV infection induces production of ROS, which potentiate signaling from pattern recognition receptors: role for S-glutathionylation of TRAF3 and 6.

by Regina Gonzalez-Dosal, Kristy A Horan, Stine H Rahbek, Hidenori Ichijo, Zhijian J Chen, John J Mieyal, Rune Hartmann, Søren R Paludan
Published 2011-09-01

MAVS-mediated apoptosis and its inhibition by viral proteins.

by Yu Lei, Chris B Moore, Rachael M Liesman, Brian P O'Connor, Daniel T Bergstralh, Zhijian J Chen, Raymond J Pickles, Jenny P-Y Ting
Published 2009-01-01

Correction: Structural basis for the prion-like MAVS filaments in antiviral innate immunity

by Hui Xu, Xiaojing He, Hui Zheng, Lily J Huang, Fajian Hou, Zhiheng Yu, Michael Jason de la Cruz, Brian Borkowski, Xuewu Zhang, Zhijian J Chen, Qiu-Xing Jiang
Published 2015-08-01

Structural basis for the prion-like MAVS filaments in antiviral innate immunity

by Hui Xu, Xiaojing He, Hui Zheng, Lily J Huang, Fajian Hou, Zhiheng Yu, Michael Jason de la Cruz, Brian Borkowski, Xuewu Zhang, Zhijian J Chen, Qiu-Xing Jiang
Published 2014-02-01

Innate immune response to Streptococcus pyogenes depends on the combined activation of TLR13 and TLR2.

by Christina Fieber, Marton Janos, Tina Koestler, Nina Gratz, Xiao-Dong Li, Virginia Castiglia, Marion Aberle, Martina Sauert, Mareike Wegner, Lena Alexopoulou, Carsten J Kirschning, Zhijian J Chen, Arndt von Haeseler, Pavel Kovarik
Published 2015-01-01

Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication.

by Sharon K Kuss-Duerkop, Juan Wang, Ignacio Mena, Kris White, Giorgi Metreveli, Ramanavelan Sakthivel, Miguel A Mata, Raquel Muñoz-Moreno, Xiang Chen, Florian Krammer, Michael S Diamond, Zhijian J Chen, Adolfo García-Sastre, Beatriz M A Fontoura
Published 2017-09-01