Ubiquitin and ubiquitin-like molecules in DNA double strand break repair

by Jia Yu, Bo Qin, Zhenkun Lou
Published 2020-02-01

The long non-coding RNA GAS5 cooperates with the eukaryotic translation initiation factor 4E to regulate c-Myc translation.

by Guangzhen Hu, Zhenkun Lou, Mamta Gupta
Published 2014-01-01

DNA end resection and its role in DNA replication and DSB repair choice in mammalian cells

by Fei Zhao, Wootae Kim, Jake A. Kloeber, Zhenkun Lou
Published 2020-10-01

Bora downregulation results in radioresistance by promoting repair of double strand breaks.

by Junmei Cairns, Yi Peng, Vivien C Yee, Zhenkun Lou, Liewei Wang
Published 2015-01-01

The necessity for standardization of glioma stem cell culture: a systematic review

by Lei Zhang, Hongwei Yu, Yuhui Yuan, John S. Yu, Zhenkun Lou, Yixue Xue, Yunhui Liu
Published 2020-02-01

KAP1 Deacetylation by SIRT1 Promotes Non-Homologous End-Joining Repair.

by Yi-Hui Lin, Jian Yuan, Huadong Pei, Tongzheng Liu, David K Ann, Zhenkun Lou
Published 2015-01-01

UFL1 promotes histone H4 ufmylation and ATM activation

by Bo Qin, Jia Yu, Somaira Nowsheen, Minghui Wang, Xinyi Tu, Tongzheng Liu, Honglin Li, Liewei Wang, Zhenkun Lou
Published 2019-03-01

USP13 regulates the RAP80-BRCA1 complex dependent DNA damage response

by Yunhui Li, Kuntian Luo, Yujiao Yin, Chenming Wu, Min Deng, Lei Li, Yuping Chen, Somaira Nowsheen, Zhenkun Lou, Jian Yuan
Published 2017-06-01

SARS-CoV-2 non-structural protein 13 (nsp13) hijacks host deubiquitinase USP13 and counteracts host antiviral immune response

by Guijie Guo, Ming Gao, Xiaochen Gao, Bibo Zhu, Jinzhou Huang, Kuntian Luo, Yong Zhang, Jie Sun, Min Deng, Zhenkun Lou
Published 2021-03-01

Regulation of Serine-Threonine Kinase Akt Activation by NAD+-Dependent Deacetylase SIRT7

by Jia Yu, Bo Qin, Fengying Wu, Sisi Qin, Somaira Nowsheen, Shan Shan, Jacqueline Zayas, Huadong Pei, Zhenkun Lou, Liewei Wang
Published 2017-01-01

Carnitine Palmitoyltransferase 1A Has a Lysine Succinyltransferase Activity

by Kiran Kurmi, Sadae Hitosugi, Elizabeth K. Wiese, Felix Boakye-Agyeman, Wilson I. Gonsalves, Zhenkun Lou, Larry M. Karnitz, Matthew P. Goetz, Taro Hitosugi
Published 2018-02-01

DBC1 Functions as a Tumor Suppressor by Regulating p53 Stability

by Bo Qin, Katherine Minter-Dykhouse, Jia Yu, Jun Zhang, Tongzheng Liu, Haoxing Zhang, SeungBaek Lee, JungJin Kim, Liewei Wang, Zhenkun Lou
Published 2015-03-01

ZFP161 regulates replication fork stability and maintenance of genomic stability by recruiting the ATR/ATRIP complex

by Wootae Kim, Fei Zhao, Rentian Wu, Sisi Qin, Somaira Nowsheen, Jinzhou Huang, Qin Zhou, Yuping Chen, Min Deng, Guijie Guo, Kuntian Luo, Zhenkun Lou, Jian Yuan
Published 2019-11-01

USP52 regulates DNA end resection and chemosensitivity through removing inhibitory ubiquitination from CtIP

by Ming Gao, Guijie Guo, Jinzhou Huang, Jake A. Kloeber, Fei Zhao, Min Deng, Xinyi Tu, Wootae Kim, Qin Zhou, Chao Zhang, Ping Yin, Kuntian Luo, Zhenkun Lou
Published 2020-10-01

ZNF506-dependent positive feedback loop regulates H2AX signaling after DNA damage

by Somaira Nowsheen, Khaled Aziz, Kuntian Luo, Min Deng, Bo Qin, Jian Yuan, Karthik B. Jeganathan, Jia Yu, Henan Zhang, Wei Ding, Jan M. van Deursen, Zhenkun Lou
Published 2018-07-01

LRRK2 inhibition potentiates PARP inhibitor cytotoxicity through inhibiting homologous recombination‐mediated DNA double strand break repair

by Lifeng Chen, Jing Hou, Xiangyu Zeng, Qiang Guo, Min Deng, Jake A Kloeber, Xinyi Tu, Fei Zhao, Zheming Wu, Jinzhou Huang, Kuntian Luo, Wootae Kim, Zhenkun Lou
Published 2021-03-01

The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair

by Qin Zhou, Jinzhou Huang, Chao Zhang, Fei Zhao, Wootae Kim, Xinyi Tu, Yong Zhang, Somaira Nowsheen, Qian Zhu, Min Deng, Yuping Chen, Bo Qin, Kuntian Luo, Baohua Liu, Zhenkun Lou, Robert W. Mutter, Jian Yuan
Published 2020-05-01

Corrigendum: An FGFR/AKT/SOX2 Signaling Axis Controls Pancreatic Cancer Stemness

by Mei-Yu Quan, Qiang Guo, Jiayu Liu, Ruo Yang, Jing Bai, Wei Wang, Yaxin Cai, Rui Han, Yu-Qing Lv, Li Ding, Daniel D. Billadeau, Zhenkun Lou, Saverio Bellusci, Saverio Bellusci, Xiaokun Li, Jin-San Zhang, Jin-San Zhang
Published 2020-10-01

An FGFR/AKT/SOX2 Signaling Axis Controls Pancreatic Cancer Stemness

by Mei-Yu Quan, Qiang Guo, Jiayu Liu, Ruo Yang, Jing Bai, Wei Wang, Yaxin Cai, Rui Han, Yu-Qing Lv, Li Ding, Daniel D. Billadeau, Zhenkun Lou, Saverio Bellusci, Saverio Bellusci, Xiaokun Li, Jin-San Zhang, Jin-San Zhang
Published 2020-05-01

Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling

by Guijie Guo, Ming Gao, Xiaochen Gao, Bibo Zhu, Jinzhou Huang, Xinyi Tu, Wootae Kim, Fei Zhao, Qin Zhou, Shouhai Zhu, Zheming Wu, Yuanliang Yan, Yong Zhang, Xiangyu Zeng, Qian Zhu, Ping Yin, Kuntian Luo, Jie Sun, Min Deng, Zhenkun Lou
Published 2021-04-01