Neutralizing Antibody Response to Hepatitis C Virus

by Zhen-Yong Keck, Yong Wang, Steven K. H. Foung
Published 2011-11-01

Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape.

by Thomas Krey, Annalisa Meola, Zhen-Yong Keck, Laurence Damier-Piolle, Steven K H Foung, Felix A Rey
Published 2013-01-01

Designing a B Cell-Based Vaccine against a Highly Variable Hepatitis C Virus

by Thomas R. Fuerst, Thomas R. Fuerst, Brian G. Pierce, Brian G. Pierce, Zhen-Yong Keck, Steven K. H. Foung
Published 2018-01-01

Non-random escape pathways from a broadly neutralizing human monoclonal antibody map to a highly conserved region on the hepatitis C virus E2 glycoprotein encompassing amino acids...

by Zhen-yong Keck, Allan G N Angus, Wenyan Wang, Patrick Lau, Yong Wang, Derek Gatherer, Arvind H Patel, Steven K H Foung
Published 2014-08-01

Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolate.

by Zhen-yong Keck, Jinming Xia, Yong Wang, Wenyan Wang, Thomas Krey, Jannick Prentoe, Thomas Carlsen, Angela Ying-Jian Li, Arvind H Patel, Stanley M Lemon, Jens Bukh, Felix A Rey, Steven K H Foung
Published 2012-01-01

Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis C virus infections uncover molecular determinants for E2 targeting and vaccine design.

by Zhen-Yong Keck, Brian G Pierce, Patrick Lau, Janine Lu, Yong Wang, Alexander Underwood, Rowena A Bull, Jannick Prentoe, Rodrigo Velázquez-Moctezuma, Melanie R Walker, Fabio Luciani, Johnathan D Guest, Catherine Fauvelle, Thomas F Baumert, Jens Bukh, Andrew R Lloyd, Steven K H Foung
Published 2019-05-01

Hepatitis C Virus (HCV)–Apolipoprotein Interactions and Immune Evasion and Their Impact on HCV Vaccine Design

by Florian Wrensch, Florian Wrensch, Emilie Crouchet, Emilie Crouchet, Gaetan Ligat, Gaetan Ligat, Mirjam B. Zeisel, Mirjam B. Zeisel, Mirjam B. Zeisel, Zhen-Yong Keck, Steven K. H. Foung, Catherine Schuster, Catherine Schuster, Thomas F. Baumert, Thomas F. Baumert, Thomas F. Baumert, Thomas F. Baumert
Published 2018-06-01

Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site

by Katie A. Howell, Xiangguo Qiu, Jennifer M. Brannan, Christopher Bryan, Edgar Davidson, Frederick W. Holtsberg, Anna Z. Wec, Sergey Shulenin, Julia E. Biggins, Robin Douglas, Sven G. Enterlein, Hannah L. Turner, Jesper Pallesen, Charles D. Murin, Shihua He, Andrea Kroeker, Hong Vu, Andrew S. Herbert, Marnie L. Fusco, Elisabeth K. Nyakatura, Jonathan R. Lai, Zhen-Yong Keck, Steven K.H. Foung, Erica Ollmann Saphire, Larry Zeitlin, Andrew B. Ward, Kartik Chandran, Benjamin J. Doranz, Gary P. Kobinger, John M. Dye, M. Javad Aman
Published 2016-05-01