Identification of Bichalcones as Sirtuin Inhibitors by Virtual Screening and In Vitro Testing

by Berin Karaman, Zayan Alhalabi, Sören Swyter, Shetonde O. Mihigo, Kerstin Andrae-Marobela, Manfred Jung, Wolfgang Sippl, Fidele Ntie-Kang
Published 2018-02-01

Sirtuin 1 Inhibiting Thiocyanates (S1th)—A New Class of Isotype Selective Inhibitors of NAD+ Dependent Lysine Deacetylases

by Nathalie Wössner, Zayan Alhalabi, Jessica González, Sören Swyter, Jin Gan, Karin Schmidtkunz, Lin Zhang, Alejandro Vaquero, Huib Ovaa, Oliver Einsle, Wolfgang Sippl, Manfred Jung
Published 2020-04-01