PD-1 and CTLA-4 up regulation on donor T cells is insufficient to prevent GvHD in allo-HSCT recipients.

by Mohammad S Hossain, Ghada M Kunter, Vicky F El-Najjar, David L Jaye, Zaid Al-Kadhimi, Owonikoko K Taofeek, Jian-Ming Li, Edmund K Waller
Published 2017-01-01

Phase II clinical trial using anti-CD3 × anti-HER2 bispecific antibody armed activated T cells (HER2 BATs) consolidation therapy for HER2 negative (0–2+) metastatic breast cancer...

by Michael Simon, Lawrence Flaherty, Lawrence G. Lum, Archana Thakur, Abhinav Deol, Kristie Fields, Dana Schalk, Zaid Al-Kadhimi, Vidya Kondadasula, Elyse Tomashewski, Patricia Steele, Melissa Giroux
Published 2021-06-01