Activation of DAF-16/FOXO by reactive oxygen species contributes to longevity in long-lived mitochondrial mutants in Caenorhabditis elegans.

by Megan M Senchuk, Dylan J Dues, Claire E Schaar, Benjamin K Johnson, Zachary B Madaj, Megan J Bowman, Mary E Winn, Jeremy M Van Raamsdonk
Published 2018-03-01

Kinome Profiling of NF1-Related MPNSTs in Response to Kinase Inhibition and Doxorubicin Reveals Therapeutic Vulnerabilities

by Jamie L. Grit, Matt G. Pridgeon, Curt J. Essenburg, Emily Wolfrum, Zachary B. Madaj, Lisa Turner, Julia Wulfkuhle, Emanuel F. Petricoin, Carrie R. Graveel, Matthew R. Steensma
Published 2020-03-01

Phosphorylation of TXNIP by AKT Mediates Acute Influx of Glucose in Response to Insulin

by Althea N. Waldhart, Holly Dykstra, Anderson S. Peck, Elissa A. Boguslawski, Zachary B. Madaj, Jennifer Wen, Kelsey Veldkamp, Matthew Hollowell, Bin Zheng, Lewis C. Cantley, Timothy E. McGraw, Ning Wu
Published 2017-06-01

Independent validation of experimental results requires timely and unrestricted access to animal models and reagents.

by Cassandra R Diegel, Steven Hann, Ugur M Ayturk, Jennifer C W Hu, Kyung-Eun Lim, Casey J Droscha, Zachary B Madaj, Gabrielle E Foxa, Isaac Izaguirre, VAI Vivarium and Transgenics Core, Alexander G Robling, Matthew L Warman, Bart O Williams
Published 2020-06-01

Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor

by Maggie H Chasse, Benjamin K Johnson, Elissa A Boguslawski, Katie M Sorensen, Jessica E Rosien, Min H Kang, C Patrick Reynolds, Lyong Heo, Zachary B Madaj, Ian Beddows, Gabrielle E Foxa, Susan M Kitchen‐Goosen, Bart O Williams, Timothy J Triche Jr, Patrick J Grohar
Published 2021-02-01

An osteocalcin-deficient mouse strain without endocrine abnormalities.

by Cassandra R Diegel, Steven Hann, Ugur M Ayturk, Jennifer C W Hu, Kyung-Eun Lim, Casey J Droscha, Zachary B Madaj, Gabrielle E Foxa, Isaac Izaguirre, Vai Vivarium And Transgenics Core, Noorulain Paracha, Bohdan Pidhaynyy, Terry L Dowd, Alexander G Robling, Matthew L Warman, Bart O Williams
Published 2020-05-01