SARS‐CoV‐2, an evolutionary perspective of interaction with human ACE2 reveals undiscovered amino acids necessary for complex stability

by Vinicio Armijos‐Jaramillo, Justin Yeager, Claire Muslin, Yunierkis Perez‐Castillo
Published 2020-10-01

The dilemma of bacterial expansins evolution. The unusual case of Streptomyces acidiscabies and Kutzneria sp. 744

by Vinicio Armijos-Jaramillo, Daniela Santander-Gordón, Eduardo Tejera, Yunierkis Perez-Castillo
Published 2018-11-01

A Multi-Objective Approach for Drug Repurposing in Preeclampsia

by Eduardo Tejera, Yunierkis Pérez-Castillo, Andrea Chamorro, Alejandro Cabrera-Andrade, Maria Eugenia Sanchez
Published 2021-02-01

A population-based study of preeclampsia and eclampsia in Ecuador: ethnic, geographical and altitudes differences

by Eduardo Tejera, Maria Eugenia Sánchez, Aquiles R. Henríquez-Trujillo, Yunierkis Pérez-Castillo, Marco Coral-Almeida
Published 2021-02-01

Alkyl and Aryl Derivatives Based on <i>p</i>-Coumaric Acid Modification and Inhibitory Action against <i>Leishmania braziliensis</i> and <i>Plasmodium falciparum</i>

by Susiany P. Lopes, Lina M. Yepes, Yunierkis Pérez-Castillo, Sara M. Robledo, Damião P. de Sousa
Published 2020-07-01

Larvicidal Activity of Cinnamic Acid Derivatives: Investigating Alternative Products for <i>Aedes aegypti</i> L. Control

by Marianna O. Araújo, Yunierkis Pérez-Castillo, Louise H. G. Oliveira, Fabíola C. Nunes, Damião P. de Sousa
Published 2021-12-01

Quinolinecarboxamides Inhibit the Replication of the Bovine Viral Diarrhea Virus by Targeting a Hot Spot for the Inhibition of Pestivirus Replication in the RNA-Dependent RNA Polym...

by Simone Musiu, Yunierkis Perez Castillo, Alexandra Muigg, Gerhard Pürstinger, Pieter Leyssen, Mathy Froeyen, Johan Neyts, Jan Paeshuyse
Published 2020-03-01

ShadowCaster: Compositional Methods under the Shadow of Phylogenetic Models to Detect Horizontal Gene Transfers in Prokaryotes

by Daniela Sánchez-Soto, Guillermin Agüero-Chapin, Vinicio Armijos-Jaramillo, Yunierkis Perez-Castillo, Eduardo Tejera, Agostinho Antunes, Aminael Sánchez-Rodríguez
Published 2020-07-01

Bioactive Terpenes and Their Derivatives as Potential SARS-CoV-2 Proteases Inhibitors from Molecular Modeling Studies

by Lúcio Ricardo Leite Diniz, Yunierkis Perez-Castillo, Hatem A. Elshabrawy, Carlos da Silva Maia Bezerra Filho, Damião Pergentino de Sousa
Published 2021-01-01

An alignment-free approach for eukaryotic ITS2 annotation and phylogenetic inference.

by Guillermin Agüero-Chapin, Aminael Sánchez-Rodríguez, Pedro I Hidalgo-Yanes, Yunierkis Pérez-Castillo, Reinaldo Molina-Ruiz, Kathleen Marchal, Vítor Vasconcelos, Agostinho Antunes
Published 2011-01-01

A Multi-Objective Approach for Anti-Osteosarcoma Cancer Agents Discovery through Drug Repurposing

by Alejandro Cabrera-Andrade, Andrés López-Cortés, Gabriela Jaramillo-Koupermann, Humberto González-Díaz, Alejandro Pazos, Cristian R. Munteanu, Yunierkis Pérez-Castillo, Eduardo Tejera
Published 2020-11-01

A desirability-based multi objective approach for the virtual screening discovery of broad-spectrum anti-gastric cancer agents.

by Yunierkis Perez-Castillo, Aminael Sánchez-Rodríguez, Eduardo Tejera, Maykel Cruz-Monteagudo, Fernanda Borges, M Natália D S Cordeiro, Huong Le-Thi-Thu, Hai Pham-The
Published 2018-01-01

Gene Prioritization through Consensus Strategy, Enrichment Methodologies Analysis, and Networking for Osteosarcoma Pathogenesis

by Alejandro Cabrera-Andrade, Andrés López-Cortés, Gabriela Jaramillo-Koupermann, César Paz-y-Miño, Yunierkis Pérez-Castillo, Cristian R. Munteanu, Humbert González-Díaz, Alejandro Pazos, Eduardo Tejera
Published 2020-02-01

NFBTA: A Potent Cytotoxic Agent against Glioblastoma

by Hasan Turkez, Flávio Rogério da Nóbrega, Ozlem Ozdemir, Carlos da Silva Maia Bezerra Filho, Reinaldo Nóbrega de Almeida, Eduardo Tejera, Yunierkis Perez-Castillo, Damião Pergentino de Sousa
Published 2019-06-01

Consensus strategy in genes prioritization and combined bioinformatics analysis for preeclampsia pathogenesis

by Eduardo Tejera, Maykel Cruz-Monteagudo, Germán Burgos, María-Eugenia Sánchez, Aminael Sánchez-Rodríguez, Yunierkis Pérez-Castillo, Fernanda Borges, Maria Natália Dias Soeiro Cordeiro, César Paz-y-Miño, Irene Rebelo
Published 2017-08-01

Bioactivity and Molecular Docking Studies of Derivatives from Cinnamic and Benzoic Acids

by Yunierkis Perez-Castillo, Tamires C. Lima, Alana R. Ferreira, Cecília R. Silva, Rosana S. Campos, João B. A. Neto, Hemerson I. F. Magalhães, Bruno C. Cavalcanti, Hélio V. N. Júnior, Damião P. de Sousa
Published 2020-01-01

In silico Analyses of Immune System Protein Interactome Network, Single-Cell RNA Sequencing of Human Tissues, and Artificial Neural Networks Reveal Potential Therapeutic Targets fo...

by Andrés López-Cortés, Andrés López-Cortés, Andrés López-Cortés, Patricia Guevara-Ramírez, Nikolaos C. Kyriakidis, Carlos Barba-Ostria, Ángela León Cáceres, Ángela León Cáceres, Ángela León Cáceres, Santiago Guerrero, Esteban Ortiz-Prado, Cristian R. Munteanu, Cristian R. Munteanu, Cristian R. Munteanu, Eduardo Tejera, Doménica Cevallos-Robalino, Ana María Gómez-Jaramillo, Katherine Simbaña-Rivera, Adriana Granizo-Martínez, Gabriela Pérez-M, Silvana Moreno, Jennyfer M. García-Cárdenas, Ana Karina Zambrano, Ana Karina Zambrano, Yunierkis Pérez-Castillo, Alejandro Cabrera-Andrade, Alejandro Cabrera-Andrade, Lourdes Puig San Andrés, Carolina Proaño-Castro, Jhommara Bautista, Andreina Quevedo, Nelson Varela, Nelson Varela, Luis Abel Quiñones, Luis Abel Quiñones, César Paz-y-Miño
Published 2021-02-01