Dissecting super-enhancer hierarchy based on chromatin interactions

by Jialiang Huang, Kailong Li, Wenqing Cai, Xin Liu, Yuannyu Zhang, Stuart H. Orkin, Jian Xu, Guo-Cheng Yuan
Published 2018-03-01

Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing

by Kailong Li, Yuxuan Liu, Hui Cao, Yuannyu Zhang, Zhimin Gu, Xin Liu, Andy Yu, Pranita Kaphle, Kathryn E. Dickerson, Min Ni, Jian Xu
Published 2020-01-01

Multiplexed capture of spatial configuration and temporal dynamics of locus-specific 3D chromatin by biotinylated dCas9

by Xin Liu, Yong Chen, Yuannyu Zhang, Yuxuan Liu, Nan Liu, Giovanni A. Botten, Hui Cao, Stuart H. Orkin, Michael Q. Zhang, Jian Xu
Published 2020-03-01

Discovering How Heme Controls Genome Function Through Heme-omics

by Ruiqi Liao, Ye Zheng, Xin Liu, Yuannyu Zhang, Gretchen Seim, Nobuyuki Tanimura, Gary M. Wilson, Peiman Hematti, Joshua J. Coon, Jing Fan, Jian Xu, Sunduz Keles, Emery H. Bresnick
Published 2020-06-01

A unified model of human hemoglobin switching through single-cell genome editing

by Yong Shen, Jeffrey M. Verboon, Yuannyu Zhang, Nan Liu, Yoon Jung Kim, Samantha Marglous, Satish K. Nandakumar, Richard A. Voit, Claudia Fiorini, Ayesha Ejaz, Anindita Basak, Stuart H. Orkin, Jian Xu, Vijay G. Sankaran
Published 2021-08-01

Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9Research in the context

by Li-shu Zhang, Xunlei Kang, Jianming Lu, Yuannyu Zhang, Xiaofeng Wu, Guojin Wu, Junke Zheng, Rubina Tuladhar, Heping Shi, Qiaoling Wang, Lorraine Morlock, Huiyu Yao, Lily Jun-shen Huang, Pascal Maire, James Kim, Noelle Williams, Jian Xu, Chuo Chen, Cheng Cheng Zhang, Lawrence Lum
Published 2019-01-01