The Role of Proteasomes in the Thymus

by Melina Frantzeskakis, Yousuke Takahama, Izumi Ohigashi
Published 2021-03-01

Identification of the transgenic integration site in immunodeficient tgε26 human CD3ε transgenic mice.

by Izumi Ohigashi, Yuki Yamasaki, Tsukasa Hirashima, Yousuke Takahama
Published 2010-01-01

Postnatal Involution and Counter-Involution of the Thymus

by Jennifer E. Cowan, Yousuke Takahama, Avinash Bhandoola, Izumi Ohigashi
Published 2020-05-01

In situ patrolling of regulatory T cells is essential for protecting autoimmune exocrinopathy.

by Naozumi Ishimaru, Takeshi Nitta, Rieko Arakaki, Akiko Yamada, Martin Lipp, Yousuke Takahama, Yoshio Hayashi
Published 2010-01-01

MiCASA is a new method for quantifying cellular organization

by Andrew Sornborger, Jie Li, Cullen Timmons, Floria Lupu, Jonathan Eggenschwiler, Yousuke Takahama, Nancy R. Manley
Published 2017-05-01

IAN family critically regulates survival and development of T lymphocytes.

by Takeshi Nitta, Mariam Nasreen, Takafumi Seike, Atsushi Goji, Izumi Ohigashi, Tadaaki Miyazaki, Tsutomu Ohta, Masamoto Kanno, Yousuke Takahama
Published 2006-04-01

Cell-autonomous defects in thymic epithelial cells disrupt endothelial-perivascular cell interactions in the mouse thymus.

by Jerrod L Bryson, Ann V Griffith, Bernard Hughes, Fumi Saito, Yousuke Takahama, Ellen R Richie, Nancy R Manley
Published 2013-01-01

Adult Thymic Medullary Epithelium Is Maintained and Regenerated by Lineage-Restricted Cells Rather Than Bipotent Progenitors

by Izumi Ohigashi, Saulius Zuklys, Mie Sakata, Carlos E. Mayer, Yoko Hamazaki, Nagahiro Minato, Georg A. Hollander, Yousuke Takahama
Published 2015-11-01

A Distinct Subset of Fibroblastic Stromal Cells Constitutes the Cortex-Medulla Boundary Subcompartment of the Lymph Node

by Arata Takeuchi, Madoka Ozawa, Yasuhiro Kanda, Mina Kozai, Izumi Ohigashi, Yoichi Kurosawa, Md Azizur Rahman, Toshihiko Kawamura, Toshihiko Kawamura, Yuto Shichida, Eiji Umemoto, Masayuki Miyasaka, Masayuki Miyasaka, Masayuki Miyasaka, Burkhard Ludewig, Yousuke Takahama, Yousuke Takahama, Takashi Nagasawa, Tomoya Katakai
Published 2018-10-01

Myc controls a distinct transcriptional program in fetal thymic epithelial cells that determines thymus growth

by Jennifer E. Cowan, Justin Malin, Yongge Zhao, Mina O. Seedhom, Christelle Harly, Izumi Ohigashi, Michael Kelly, Yousuke Takahama, Jonathan W. Yewdell, Maggie Cam, Avinash Bhandoola
Published 2019-12-01

Foxn1-β5t transcriptional axis controls CD8+ T-cell production in the thymus

by Muhammad Myn Uddin, Izumi Ohigashi, Ryo Motosugi, Tomomi Nakayama, Mie Sakata, Jun Hamazaki, Yasumasa Nishito, Immanuel Rode, Keiji Tanaka, Tatsuya Takemoto, Shigeo Murata, Yousuke Takahama
Published 2017-02-01

Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells

by Beth Lucas, Andrea J. White, Emilie J. Cosway, Sonia M. Parnell, Kieran D. James, Nick D. Jones, Izumi Ohigashi, Yousuke Takahama, William E. Jenkinson, Graham Anderson
Published 2020-05-01

Radiation inducible MafB gene is required for thymic regeneration

by Daiki Hashimoto, Jose Gabriel R. Colet, Aki Murashima, Kota Fujimoto, Yuko Ueda, Kentaro Suzuki, Taiju Hyuga, Hiroaki Hemmi, Tsuneyasu Kaisho, Satoru Takahashi, Yousuke Takahama, Gen Yamada
Published 2021-05-01

Epigenetic Protection of Vertebrate Lymphoid Progenitor Cells by Dnmt1

by Norimasa Iwanami, Kohei Takeshita, Divine-Fondzenyuy Lawir, Isao Suetake, Shoji Tajima, Katarzyna Sikora, Inês Trancoso, Connor ÓMeara, Iliana Siamishi, Yousuke Takahama, Makoto Furutani-Seiki, Hisato Kondoh, Yasushige Yonezawa, Michael Schorpp, Thomas Boehm
Published 2020-07-01

Trans-omics Impact of Thymoproteasome in Cortical Thymic Epithelial Cells

by Izumi Ohigashi, Yu Tanaka, Kenta Kondo, Sayumi Fujimori, Hiroyuki Kondo, Amy C. Palin, Victoria Hoffmann, Mina Kozai, Yosuke Matsushita, Shinsuke Uda, Ryo Motosugi, Jun Hamazaki, Hiroyuki Kubota, Shigeo Murata, Keiji Tanaka, Toyomasa Katagiri, Hidetaka Kosako, Yousuke Takahama
Published 2019-11-01

WDR55 is a nucleolar modulator of ribosomal RNA synthesis, cell cycle progression, and teleost organ development.

by Norimasa Iwanami, Tomokazu Higuchi, Yumi Sasano, Toshinobu Fujiwara, Vu Q Hoa, Minoru Okada, Sadiqur R Talukder, Sanae Kunimatsu, Jie Li, Fumi Saito, Chitralekha Bhattacharya, Angabin Matin, Takashi Sasaki, Nobuyoshi Shimizu, Hiroshi Mitani, Heinz Himmelbauer, Akihiro Momoi, Hisato Kondoh, Makoto Furutani-Seiki, Yousuke Takahama
Published 2008-08-01

Correction: WDR55 Is a Nucleolar Modulator of Ribosomal RNA Synthesis, Cell Cycle Progression, and Teleost Organ Development

by Norimasa Iwanami, Tomokazu Higuchi, Yumi Sasano, Toshinobu Fujiwara, Vu Q. Hoa, Minoru Okada, Sadiqur R. Talukder, Sanae Kunimatsu, Jie Li, Fumi Saito, Chitralekha Bhattacharya, Angabin Matin, Takashi Sasaki, Nobuyoshi Shimizu, Hiroshi Mitani, Heinz Himmelbauer, Akihiro Momoi, Hisato Kondoh, Makoto Furutani-Seiki, Yousuke Takahama
Published 2008-09-01

Correction: WDR55 Is a Nucleolar Modulator of Ribosomal RNA Synthesis, Cell Cycle Progression, and Teleost Organ Development.

by Norimasa Iwanami, Tomokazu Higuchi, Yumi Sasano, Toshinobu Fujiwara, Vu Q. Hoa, Minoru Okada, Sadiqur R. Talukder, Sanae Kunimatsu, Jie Li, Fumi Saito, Chitralekha Bhattacharya, Angabin Matin, Takashi Sasaki, Nobuyoshi Shimizu, Hiroshi Mitani, Heinz Himmelbauer, Akihiro Momoi, Hisato Kondoh, Makoto Furutani-Seiki, Yousuke Takahama
Published 2008-09-01