The endothelial dysfunction blocker CU06-1004 ameliorates choline-deficient L-amino acid diet-induced non-alcoholic steatohepatitis in mice.

by Cho-Rong Bae, Haiying Zhang, Young-Guen Kwon
Published 2020-01-01

Regulation of ROS Production and Vascular Function by Carbon Monoxide

by Yoon Kyung Choi, Elaine D. Por, Young-Guen Kwon, Young-Myeong Kim
Published 2012-01-01

Endothelial Snail Regulates Capillary Branching Morphogenesis via Vascular Endothelial Growth Factor Receptor 3 Expression.

by Jeong Ae Park, Dong Young Kim, Young-Myeong Kim, In-Kyu Lee, Young-Guen Kwon
Published 2015-07-01

Primaquine Diphosphate, a Known Antimalarial Drug, Blocks Vascular Leakage Acting Through Junction Stabilization

by Minyoung Noh, Haiying Zhang, Hyejeong Kim, Songyi Park, Young-Myeong Kim, Young-Guen Kwon
Published 2021-06-01

CU06-1004 Alleviates Experimental Colitis by Modulating Colonic Vessel Dysfunction

by Ye-Seul Kim, Haiying Zhang, Sunghye Lee, Songyi Park, Minyoung Noh, Young-Myeong Kim, Young-Guen Kwon
Published 2020-09-01

A novel sLRP6E1E2 inhibits canonical Wnt signaling, epithelial-to-mesenchymal transition, and induces mitochondria-dependent apoptosis in lung cancer.

by Jung-Sun Lee, Man-Wook Hur, Seong Kyung Lee, Won-Il Choi, Young-Guen Kwon, Chae-Ok Yun
Published 2012-01-01

Rk1, a ginsenoside, is a new blocker of vascular leakage acting through actin structure remodeling.

by Yong-Sun Maeng, Sony Maharjan, Jeong-Hun Kim, Jeong-Hill Park, Young Suk Yu, Young-Myoung Kim, Young-Guen Kwon
Published 2013-01-01

CLEC14A deficiency exacerbates neuronal loss by increasing blood-brain barrier permeability and inflammation

by Yeomyeong Kim, Sungwoon Lee, Haiying Zhang, Sunghye Lee, Hyejeong Kim, Yeaji Kim, Moo-Ho Won, Young-Myeong Kim, Young-Guen Kwon
Published 2020-02-01

Korean Red ginseng prevents endothelial senescence by downregulating the HO-1/NF-κB/miRNA-155-5p/eNOS pathway

by Tae-Hoon Kim, Ji-Yoon Kim, Jieun Bae, Young-Mi Kim, Moo-Ho Won, Kwon-Soo Ha, Young-Guen Kwon, Young-Myeong Kim
Published 2021-03-01

Circulating miRNAs Associated with Dysregulated Vascular and Trophoblast Function as Target-Based Diagnostic Biomarkers for Preeclampsia

by Suji Kim, Minsik Park, Ji-Yoon Kim, Taesam Kim, Jong Yun Hwang, Kwon-Soo Ha, Moo-Ho Won, Sungwoo Ryoo, Young-Guen Kwon, Young-Myeong Kim
Published 2020-08-01

CU06-1004-Induced Vascular Normalization Improves Immunotherapy by Modulating Tumor Microenvironment via Cytotoxic T Cells

by Songyi Park, Ji Hoon Oh, Dong Jin Park, Haiying Zhang, Minyoung Noh, Yeomyung Kim, Ye-Seul Kim, Hyejeong Kim, Young-Myeong Kim, Sang-Jun Ha, Young-Guen Kwon
Published 2021-01-01

Heme oxygenase metabolites improve astrocytic mitochondrial function via a Ca2+-dependent HIF-1α/ERRα circuit.

by Yoon Kyung Choi, Joon Ha Park, Jung-A Yun, Jong-Ho Cha, Yonghee Kim, Moo-Ho Won, Kyu-Won Kim, Kwon-Soo Ha, Young-Guen Kwon, Young-Myeong Kim
Published 2018-01-01

Human plasminogen-derived N-acetyl-Arg-Leu-Tyr-Glu antagonizes VEGFR-2 to prevent blood-retinal barrier breakdown in diabetic mice

by Wonjin Park, Joohwan Kim, Seunghwan Choi, Taesam Kim, Minsik Park, Suji Kim, Ji-Chang You, Jeong Hun Kim, Kwon-Soo Ha, Jeong-Hyung Lee, Young-Guen Kwon, Young-Myeong Kim
Published 2021-02-01

Stabilization of Intrinsically Disordered DKK2 Protein by Fusion to RNA-Binding Domain

by Hye Min Lee, Soon Bin Kwon, Ahyun Son, Doo Hyun Kim, Kyun-Hwan Kim, Jonghyo Lim, Young-Guen Kwon, Jin Sun Kang, Byung Kyu Lee, Young Ho Byun, Baik L. Seong
Published 2019-06-01

Dickkopf2 rescues erectile function by enhancing penile neurovascular regeneration in a mouse model of cavernous nerve injury

by Kalyan Ghatak, Guo Nan Yin, Min-Ji Choi, Anita Limanjaya, Nguyen Nhat Minh, Jiyeon Ock, Kang-Moon Song, Dong Hyuk Kang, Young-Guen Kwon, Ho Min Kim, Ji-Kan Ryu, Jun-Kyu Suh
Published 2017-12-01

Ginseng Berry Extract Prevents Atherogenesis via Anti-Inflammatory Action by Upregulating Phase II Gene Expression

by Chun-Ki Kim, Dong Hui Cho, Kyu-Sun Lee, Dong-Keon Lee, Chan-Woong Park, Wan Gi Kim, Sang Jun Lee, Kwon-Soo Ha, Oh Goo Taeg, Young-Guen Kwon, Young-Myeong Kim
Published 2012-01-01

NF-κB-dependent miR-31/155 biogenesis is essential for TNF-α-induced impairment of endothelial progenitor cell function

by Ji-Hee Kim, Ji-Yoon Kim, Minsik Park, Suji Kim, Taesam Kim, Joohwan Kim, Seunghwan Choi, Wonjin Park, Jong Yun Hwang, Jongseon Choe, Kwon-Soo Ha, Moo-Ho Won, Sungwoo Ryoo, Young-Guen Kwon, Young-Myeong Kim
Published 2020-08-01

NF-κB-responsive miR-155 induces functional impairment of vascular smooth muscle cells by downregulating soluble guanylyl cyclase

by Minsik Park, Seunghwan Choi, Suji Kim, Joohwan Kim, Dong-Keon Lee, Wonjin Park, Taesam Kim, Jiwon Jung, Jong Yun Hwang, Moo-Ho Won, Sungwoo Ryoo, Seung Goo Kang, Kwon-Soo Ha, Young-Guen Kwon, Young-Myeong Kim
Published 2019-02-01

Sac-1004, a vascular leakage blocker, reduces cerebral ischemia—reperfusion injury by suppressing blood–brain barrier disruption and inflammation

by Haiying Zhang, Joon Ha Park, Sony Maharjan, Jeong Ae Park, Kyu-Sung Choi, Hyojin Park, Yoonjeong Jeong, Ji Hyeon Ahn, In Hye Kim, Jae-Chul Lee, Jeong Hwi Cho, In-Kyu Lee, Choong Hyun Lee, In Koo Hwang, Young-Myeong Kim, Young-Ger Suh, Moo-Ho Won, Young-Guen Kwon
Published 2017-06-01

Neuroprotective effect of a new synthetic aspirin-decursinol adduct in experimental animal models of ischemic stroke.

by Bing Chun Yan, Joon Ha Park, Bich Na Shin, Ji Hyeon Ahn, In Hye Kim, Jae-Chul Lee, Ki-Yeon Yoo, In Koo Hwang, Jung Hoon Choi, Jeong Ho Park, Yun Lyul Lee, Hong-Won Suh, Jong-Gab Jun, Young-Guen Kwon, Young-Myeong Kim, Seung-Hae Kwon, Song Her, Jin Su Kim, Byung-Hwa Hyun, Chul-Kyu Kim, Jun Hwi Cho, Choong Hyun Lee, Moo-Ho Won
Published 2013-01-01