Mechanism of Allosteric Modulation of the Cys-loop Receptors

by Paul Whiteaker, Yao Huang, Yongchang Chang
Published 2010-08-01

Novel DNA Aptamers for Parkinson’s Disease Treatment Inhibit α-Synuclein Aggregation and Facilitate its Degradation

by Yuan Zheng, Jing Qu, Fenqin Xue, Yan Zheng, Bo Yang, Yongchang Chang, Hui Yang, Jianliang Zhang
Published 2018-06-01

Structural and Functional Characterization of Two Alternative Splicing Variants of Mouse Endothelial Cell-Specific Chemotaxis Regulator (ECSCR)

by Yongchang Chang, Hong-Long Ji, Fanxin Ma, James Balducci, Hanju Huang, Chunwei Shi, Wen Wu, Yao Huang
Published 2012-04-01

Endothelial cell-specific molecule 2 (ECSM2) localizes to cell-cell junctions and modulates bFGF-directed cell migration via the ERK-FAK pathway.

by Chunwei Shi, Jia Lu, Wen Wu, Fanxin Ma, Joseph Georges, Hanju Huang, James Balducci, Yongchang Chang, Yao Huang
Published 2011-01-01

The Molecular Mechanism of Alpha-Synuclein Dependent Regulation of Protein Phosphatase 2A Activity

by Jing Qu, Hongxia Yan, Yuan Zheng, Fenqin Xue, Yan Zheng, Hongjuan Fang, Yongchang Chang, Hui Yang, Jianliang Zhang
Published 2018-07-01

Exosomal DNA Aptamer Targeting α-Synuclein Aggregates Reduced Neuropathological Deficits in a Mouse Parkinson’s Disease Model

by Xiaoxi Ren, Yun Zhao, Fenqin Xue, Yan Zheng, Haixia Huang, Wei Wang, Yongchang Chang, Hui Yang, Jianliang Zhang
Published 2019-09-01

Functional Impact of 14 Single Nucleotide Polymorphisms Causing Missense Mutations of Human α7 Nicotinic Receptor.

by Qinhui Zhang, Yingjie Du, Jianliang Zhang, Xiaojun Xu, Fenqin Xue, Cong Guo, Yao Huang, Ronald J Lukas, Yongchang Chang
Published 2015-01-01

Cocaine Directly Inhibits α6-Containing Nicotinic Acetylcholine Receptors in Human SH-EP1 Cells and Mouse VTA DA Neurons

by Dejie Chen, Dejie Chen, Fenfei Gao, Xiaokuang Ma, Xiaokuang Ma, Jason Brek Eaton, Yuanbing Huang, Yuanbing Huang, Ming Gao, Yongchang Chang, Zegang Ma, Taleen Der-Ghazarian, Janet Neisewander, Paul Whiteaker, Jie Wu, Jie Wu, Jie Wu, Quanxi Su
Published 2019-02-01