RRM domain of ALS/FTD-causing FUS characteristic of irreversible unfolding spontaneously self-assembles into amyloid fibrils

by Yimei Lu, Liangzhong Lim, Jianxing Song
Published 2017-04-01

A unified mechanism for LLPS of ALS/FTLD-causing FUS as well as its modulation by ATP and oligonucleic acids.

by Jian Kang, Liangzhong Lim, Yimei Lu, Jianxing Song
Published 2019-06-01

ALS-Causing Mutations Significantly Perturb the Self-Assembly and Interaction with Nucleic Acid of the Intrinsically Disordered Prion-Like Domain of TDP-43.

by Liangzhong Lim, Yuanyuan Wei, Yimei Lu, Jianxing Song
Published 2016-01-01

Solution conformations of Zika NS2B-NS3pro and its inhibition by natural products from edible plants.

by Amrita Roy, Liangzhong Lim, Shagun Srivastava, Yimei Lu, Jianxing Song
Published 2017-01-01

Fangchinoline inhibits human immunodeficiency virus type 1 replication by interfering with gp160 proteolytic processing.

by Zhitao Wan, Yimei Lu, Qingjiao Liao, Yang Wu, Xulin Chen
Published 2012-01-01

Relieving Cellular Energy Stress in Aging, Neurodegenerative, and Metabolic Diseases, SIRT1 as a Therapeutic and Promising Node

by Yang Fang, Yang Fang, Xifeng Wang, Danying Yang, Danying Yang, Yimei Lu, Yimei Lu, Gen Wei, Gen Wei, Wen Yu, Wen Yu, Xing Liu, Xing Liu, Qingcui Zheng, Qingcui Zheng, Jun Ying, Jun Ying, Fuzhou Hua, Fuzhou Hua
Published 2021-09-01

Validation of Induced Microglia-Like Cells (iMG Cells) for Future Studies of Brain Diseases

by Atoshi Banerjee, Yimei Lu, Kenny Do, Travis Mize, Travis Mize, Xiaogang Wu, Xiaogang Wu, Xiangning Chen, Jingchun Chen
Published 2021-04-01