New insights into the Hendra virus attachment and entry process from structures of the virus G glycoprotein and its complex with Ephrin-B2.

by Kai Xu, Yee-Peng Chan, Kanagalaghatta R Rajashankar, Dimple Khetawat, Lianying Yan, Momchil V Kolev, Christopher C Broder, Dimitar B Nikolov
Published 2012-01-01

Development of an acute and highly pathogenic nonhuman primate model of Nipah virus infection.

by Thomas W Geisbert, Kathleen M Daddario-DiCaprio, Andrew C Hickey, Mark A Smith, Yee-Peng Chan, Lin-Fa Wang, Joseph J Mattapallil, Joan B Geisbert, Katharine N Bossart, Christopher C Broder
Published 2010-05-01

A neutralizing human monoclonal antibody protects against lethal disease in a new ferret model of acute nipah virus infection.

by Katharine N Bossart, Zhongyu Zhu, Deborah Middleton, Jessica Klippel, Gary Crameri, John Bingham, Jennifer A McEachern, Diane Green, Timothy J Hancock, Yee-Peng Chan, Andrew C Hickey, Dimiter S Dimitrov, Lin-Fa Wang, Christopher C Broder
Published 2009-10-01

Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly.

by Kai Xu, Yee-Peng Chan, Birgit Bradel-Tretheway, Zeynep Akyol-Ataman, Yongqun Zhu, Somnath Dutta, Lianying Yan, YanRu Feng, Lin-Fa Wang, Georgios Skiniotis, Benhur Lee, Z Hong Zhou, Christopher C Broder, Hector C Aguilar, Dimitar B Nikolov
Published 2015-12-01

Crystal structure of the Hendra virus attachment G glycoprotein bound to a potent cross-reactive neutralizing human monoclonal antibody.

by Kai Xu, Barry Rockx, Yihu Xie, Blair L DeBuysscher, Deborah L Fusco, Zhongyu Zhu, Yee-Peng Chan, Yan Xu, Truong Luu, Regina Z Cer, Heinz Feldmann, Vishwesh Mokashi, Dimiter S Dimitrov, Kimberly A Bishop-Lilly, Christopher C Broder, Dimitar B Nikolov
Published 2013-01-01