Application of ITC-Based Characterization of Thermodynamic and Kinetic Association of Ligands With Proteins in Drug Design

by Haixia Su, Haixia Su, Yechun Xu, Yechun Xu
Published 2018-10-01

Potential treatment of COVID-19 by inhibitors of human dihydroorotate dehydrogenase

by Yechun Xu, Hualiang Jiang
Published 2020-08-01

Recent Trends and Applications of Molecular Modeling in GPCR–Ligand Recognition and Structure-Based Drug Design

by Xiaojing Yuan, Yechun Xu
Published 2018-07-01

Gorge Motions of Acetylcholinesterase Revealed by Microsecond Molecular Dynamics Simulations

by Shanmei Cheng, Wanling Song, Xiaojing Yuan, Yechun Xu
Published 2017-06-01

A New Differentially-Fed Frequency Reconfigurable Antenna for WLAN and Sub-6GHz 5G Applications

by Guiping Jin, Chuhong Deng, Ju Yang, Yechun Xu, Shaowei Liao
Published 2019-01-01

Computational Studies on Acetylcholinesterases

by Yechun Xu, Shanmei Cheng, Joel L. Sussman, Israel Silman, Hualiang Jiang
Published 2017-08-01

Mechanics of channel gating of the nicotinic acetylcholine receptor.

by Xinli Liu, Yechun Xu, Honglin Li, Xicheng Wang, Hualiang Jiang, Francisco J Barrantes
Published 2008-01-01

Understanding Voltage Gating of Providencia stuartii Porins at Atomic Level.

by Wanling Song, Harsha Bajaj, Chady Nasrallah, Hualiang Jiang, Mathias Winterhalter, Jacques-Philippe Colletier, Yechun Xu
Published 2015-05-01

Virtual Screening and Structure-Based Discovery of Indole Acylguanidines as Potent β-secretase (BACE1) Inhibitors

by Bing Xiong, Yechun Xu, Jingkang Shen, Xin Wang, Lanping Ma, Tiantian Chen, Wuyan Chen, Yiquan Zou, Li Li
Published 2013-05-01

Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5

by Hui Zhang, Kun Chen, Qiuxiang Tan, Qiang Shao, Shuo Han, Chenhui Zhang, Cuiying Yi, Xiaojing Chu, Ya Zhu, Yechun Xu, Qiang Zhao, Beili Wu
Published 2021-07-01

Structure-Based Discovery of a Series of 5H-Pyrrolo[2,3-b]pyrazine FGFR Kinase Inhibitors

by Alan Jiang, Qiufeng Liu, Ruifeng Wang, Peng Wei, Yang Dai, Xin Wang, Yechun Xu, Yuchi Ma, Jing Ai, Jingkang Shen, Jian Ding, Bing Xiong
Published 2018-03-01

Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation

by Heng Li, Xianglei Zhang, Caigui Xiang, Chunlan Feng, Chen Fan, Moting Liu, Huimin Lu, Haixia Su, Yu Zhou, Qing Qi, Yechun Xu, Wei Tang
Published 2021-11-01

Structural basis of ligand binding modes at the human formyl peptide receptor 2

by Tong Chen, Muya Xiong, Xin Zong, Yunjun Ge, Hui Zhang, Mu Wang, Gye Won Han, Cuiying Yi, Limin Ma, Richard D. Ye, Yechun Xu, Qiang Zhao, Beili Wu
Published 2020-03-01

Allosteric Regulation of Hsp90α’s Activity by Small Molecules Targeting the Middle Domain of the Chaperone

by Chen Zhou, Chi Zhang, Hongwen Zhu, Zhijun Liu, Haixia Su, Xianglei Zhang, Tingting Chen, Yan Zhong, Huifang Hu, Muya Xiong, Hu Zhou, Yechun Xu, Ao Zhang, Naixia Zhang
Published 2020-02-01

Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease

by Haixia Su, Sheng Yao, Wenfeng Zhao, Yumin Zhang, Jia Liu, Qiang Shao, Qingxing Wang, Minjun Li, Hang Xie, Weijuan Shang, Changqiang Ke, Lu Feng, Xiangrui Jiang, Jingshan Shen, Gengfu Xiao, Hualiang Jiang, Leike Zhang, Yang Ye, Yechun Xu
Published 2021-06-01