Experimental Strategies to Explore Drug Action and Resistance in Kinetoplastid Parasites

by Magali Van den Kerkhof, Yann G.-J. Sterckx, Philippe Leprohon, Louis Maes, Guy Caljon
Published 2020-06-01

Development of a recombinase polymerase amplification lateral flow assay for the detection of active Trypanosoma evansi infections.

by Zeng Li, Joar Esteban Pinto Torres, Julie Goossens, Benoit Stijlemans, Yann G-J Sterckx, Stefan Magez
Published 2020-02-01

An Anti-proteome Nanobody Library Approach Yields a Specific Immunoassay for Trypanosoma congolense Diagnosis Targeting Glycosomal Aldolase.

by Steven Odongo, Yann G J Sterckx, Benoît Stijlemans, Davita Pillay, Théo Baltz, Serge Muyldermans, Stefan Magez
Published 2016-02-01

Structural basis for the high specificity of a Trypanosoma congolense immunoassay targeting glycosomal aldolase.

by Joar Pinto, Steven Odongo, Felicity Lee, Vaiva Gaspariunaite, Serge Muyldermans, Stefan Magez, Yann G-J Sterckx
Published 2017-09-01

An Unbiased Immunization Strategy Results in the Identification of Enolase as a Potential Marker for Nanobody-Based Detection of <i>Trypanosoma evansi</i>

by Zeng Li, Joar Esteban Pinto Torres, Julie Goossens, Didier Vertommen, Guy Caljon, Yann G.-J. Sterckx, Stefan Magez
Published 2020-07-01

Immunogenicity Risk Profile of Nanobodies

by Chloé Ackaert, Natalia Smiejkowska, Catarina Xavier, Yann G. J. Sterckx, Yann G. J. Sterckx, Sofie Denies, Benoit Stijlemans, Benoit Stijlemans, Yvon Elkrim, Nick Devoogdt, Vicky Caveliers, Vicky Caveliers, Tony Lahoutte, Tony Lahoutte, Serge Muyldermans, Karine Breckpot, Marleen Keyaerts, Marleen Keyaerts
Published 2021-03-01

Structural Basis for the Specific Neutralization of Stx2a with a Camelid Single Domain Antibody Fragment

by Robert Alvin Bernedo-Navarro, Ema Romão, Tomomasa Yano, Joar Pinto, Henri De Greve, Yann G.-J. Sterckx, Serge Muyldermans
Published 2018-03-01

Identification of Nanobodies against the Acute Myeloid Leukemia Marker CD33

by Ema Romão, Ahmet Krasniqi, Laila Maes, Camille Vandenbrande, Yann G.-J. Sterckx, Benoit Stijlemans, Cécile Vincke, Nick Devoogdt, Serge Muyldermans
Published 2020-01-01

The History of Anti-Trypanosome Vaccine Development Shows That Highly Immunogenic and Exposed Pathogen-Derived Antigens Are Not Necessarily Good Target Candidates: Enolase and ISG7...

by Stefan Magez, Zeng Li, Hang Thi Thu Nguyen, Joar Esteban Pinto Torres, Pieter Van Wielendaele, Magdalena Radwanska, Jakub Began, Sebastian Zoll, Yann G.-J. Sterckx
Published 2021-08-01

Development of a Nanobody-based lateral flow assay to detect active Trypanosoma congolense infections

by Joar E. Pinto Torres, Julie Goossens, Jianzu Ding, Zeng Li, Shaohong Lu, Didier Vertommen, Peter Naniima, Rui Chen, Serge Muyldermans, Yann G.-J. Sterckx, Stefan Magez
Published 2018-06-01