A Compartment-Based Mathematical Model for Studying Convective Aerosol Transport in Newborns Receiving Nebulized Drugs during Noninvasive Respiratory Support

by Francesco Tarantini, Ilaria Milesi, Xabier Murgia, Federico Bianco, Raffaele L. Dellacà
Published 2020-09-01

Itaconic Acid Increases the Efficacy of Tobramycin against <i>Pseudomonas aeruginosa</i> Biofilms

by Duy-Khiet Ho, Chiara De Rossi, Brigitta Loretz, Xabier Murgia, Claus-Michael Lehr
Published 2020-07-01

Effect of surfactant and partial liquid ventilation treatment on gas exchange and lung mechanics in immature lambs: influence of gestational age.

by Carmen Rey-Santano, Victoria Mielgo, Elena Gastiasoro, Adolfo Valls-i-Soler, Xabier Murgia
Published 2013-01-01

Synthesis and Biopharmaceutical Characterization of Amphiphilic Squalenyl Derivative Based Versatile Drug Delivery Platform

by Duy-Khiet Ho, Duy-Khiet Ho, Rebekka Christmann, Rebekka Christmann, Xabier Murgia, Xabier Murgia, Chiara De Rossi, Sarah Frisch, Sarah Frisch, Marcus Koch, Ulrich F. Schaefer, Brigitta Loretz, Didier Desmaele, Patrick Couvreur, Claus-Michael Lehr, Claus-Michael Lehr
Published 2020-10-01

Aerosol drug delivery to spontaneously-breathing preterm neonates: lessons learned

by Federico Bianco, Fabrizio Salomone, Ilaria Milesi, Xabier Murgia, Sauro Bonelli, Elena Pasini, Raffaele Dellacà, Maria Luisa Ventura, Jane Pillow
Published 2021-02-01

In Vivo Evaluation of the Acute Pulmonary Response to Poractant Alfa and Bovactant Treatments in Lung-Lavaged Adult Rabbits and in Preterm Lambs with Respiratory Distress Syndrome

by Francesca Ricci, Fabrizio Salomone, Elke Kuypers, Daan Ophelders, Maria Nikiforou, Monique Willems, Tobias Krieger, Xabier Murgia, Matthias Hütten, Boris W. Kramer, Federico Bianco
Published 2017-08-01

In Vitro Performance of an Investigational Vibrating-Membrane Nebulizer with Surfactant under Simulated, Non-Invasive Neonatal Ventilation Conditions: Influence of Continuous Posit...

by Federico Bianco, Elena Pasini, Marcello Nutini, Xabier Murgia, Carolin Stoeckl, Martin Schlun, Uwe Hetzer, Sauro Bonelli, Marta Lombardini, Ilaria Milesi, Marisa Pertile, Stefan Minocchieri, Fabrizio Salomone, Albert Bucholski
Published 2020-03-01

Extended Pharmacopeial Characterization of Surfactant Aerosols Generated by a Customized eFlow Neos Nebulizer Delivered through Neonatal Nasal Prongs

by Federico Bianco, Elena Pasini, Marcello Nutini, Xabier Murgia, Carolin Stoeckl, Martin Schlun, Uwe Hetzer, Sauro Bonelli, Marta Lombardini, Ilaria Milesi, Marisa Pertile, Stephan Minocchieri, Fabrizio Salomone, Albert Bucholski
Published 2020-04-01

Physiological, Biochemical, and Biophysical Characterization of the Lung-Lavaged Spontaneously-Breathing Rabbit as a Model for Respiratory Distress Syndrome.

by Francesca Ricci, Chiara Catozzi, Xabier Murgia, Brenda Rosa, Davide Amidani, Luca Lorenzini, Federico Bianco, Claudio Rivetti, Silvia Catinella, Gino Villetti, Maurizio Civelli, Barbara Pioselli, Carlo Dani, Fabrizio Salomone
Published 2017-01-01

A Custom-Made Device for Reproducibly Depositing Pre-metered Doses of Nebulized Drugs on Pulmonary Cells in vitro

by Justus C. Horstmann, Justus C. Horstmann, Chelsea R. Thorn, Patrick Carius, Patrick Carius, Florian Graef, Xabier Murgia, Cristiane de Souza Carvalho-Wodarz, Claus-Michael Lehr, Claus-Michael Lehr
Published 2021-04-01

Surfactant-Assisted Distal Pulmonary Distribution of Budesonide Revealed by Mass Spectrometry Imaging

by Riccardo Zecchi, Pietro Franceschi, Laura Tigli, Barbara Pioselli, Valentina Mileo, Xabier Murgia, Fabrizio Salomone, Giuseppe Pieraccini, Haruo Usada, Augusto F. Schmidt, Noah H. Hillman, Matthew W. Kemp, Alan H. Jobe
Published 2021-06-01

Mass spectrometry imaging as a tool for evaluating the pulmonary distribution of exogenous surfactant in premature lambs

by Riccardo Zecchi, Pietro Franceschi, Laura Tigli, Francesca Ricci, Francesca Boscaro, Barbara Pioselli, Valentina Mileo, Xabier Murgia, Federico Bianco, Fabrizio Salomone, Augusto F. Schmidt, Noah H. Hillman, Matthew W. Kemp, Alan H. Jobe
Published 2019-08-01

In vitro surfactant and perfluorocarbon aerosol deposition in a neonatal physical model of the upper conducting airways.

by Estibalitz Goikoetxea, Xabier Murgia, Pablo Serna-Grande, Adolf Valls-i-Soler, Carmen Rey-Santano, Alejandro Rivas, Raúl Antón, Francisco J Basterretxea, Lorena Miñambres, Estíbaliz Méndez, Alberto Lopez-Arraiza, Juan Luis Larrabe-Barrena, Miguel Angel Gomez-Solaetxe
Published 2014-01-01

A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms

by Christian Schütz, Duy‐Khiet Ho, Mostafa Mohamed Hamed, Ahmed Saad Abdelsamie, Teresa Röhrig, Christian Herr, Andreas Martin Kany, Katharina Rox, Stefan Schmelz, Lorenz Siebenbürger, Marius Wirth, Carsten Börger, Samir Yahiaoui, Robert Bals, Andrea Scrima, Wulf Blankenfeldt, Justus Constantin Horstmann, Rebekka Christmann, Xabier Murgia, Marcus Koch, Aylin Berwanger, Brigitta Loretz, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Claus‐Michael Lehr, Martin Empting
Published 2021-06-01