Immunological Properties of Murine Parthenogenetic Stem Cell-Derived Cardiomyocytes and Engineered Heart Muscle

by Michael Didié, Michael Didié, Michael Didié, Satish Galla, Vijayakumar Muppala, Ralf Dressel, Ralf Dressel, Wolfram-Hubertus Zimmermann, Wolfram-Hubertus Zimmermann
Published 2017-08-01

Generation of Engineered Human Myocardium in a Multi-well Format

by Malte Tiburcy, Tim Meyer, Norman Y. Liaw, Wolfram-Hubertus Zimmermann
Published 2020-06-01

Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression

by Eric Schoger, Wolfram-Hubertus Zimmermann, Lukas Cyganek, Laura Cecilia Zelarayán
Published 2021-08-01

Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation

by Eric Schoger, Wolfram-Hubertus Zimmermann, Lukas Cyganek, Laura Cecilia Zelarayán
Published 2021-10-01

Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation

by Eric Schoger, Loukas Argyriou, Wolfram-Hubertus Zimmermann, Lukas Cyganek, Laura Cecilia Zelarayán
Published 2020-10-01

Immunological Properties of Murine Parthenogenetic Stem Cells and Their Differentiation Products

by Hannah Johannsen, Vijayakumar Muppala, Carina Gröschel, Carina Gröschel, Sebastian Monecke, Sebastian Monecke, Leslie Elsner, Michael Didié, Michael Didié, Wolfram-Hubertus Zimmermann, Wolfram-Hubertus Zimmermann, Ralf Dressel, Ralf Dressel
Published 2017-08-01

Generation of a KLF15 homozygous knockout human embryonic stem cell line using paired CRISPR/Cas9n, and human cardiomyocytes derivation

by Claudia Noack, Luis Peter Haupt, Wolfram-Hubertus Zimmermann, Katrin Streckfuss-Bömeke, Laura Cecilia Zelarayán
Published 2017-08-01

Cardiac engraftment of genetically-selected parthenogenetic stem cell-derived cardiomyocytes.

by Tao Yang, Michael Rubart, Mark H Soonpaa, Michael Didié, Peter Christalla, Wolfram-Hubertus Zimmermann, Loren J Field
Published 2015-01-01

Optogenetic Monitoring of the Glutathione Redox State in Engineered Human Myocardium

by Irina Trautsch, Irina Trautsch, Eriona Heta, Eriona Heta, Poh Loong Soong, Poh Loong Soong, Elif Levent, Elif Levent, Viacheslav O. Nikolaev, Viacheslav O. Nikolaev, Ivan Bogeski, Ivan Bogeski, Dörthe M. Katschinski, Dörthe M. Katschinski, Manuel Mayr, Wolfram-Hubertus Zimmermann, Wolfram-Hubertus Zimmermann
Published 2019-04-01

Comparison of cine and real-time cardiac MRI in rhesus macaques

by Amir Moussavi, Sophie Mißbach, Claudia Serrano Ferrel, Hasti Ghasemipour, Kristin Kötz, Charis Drummer, Rüdiger Behr, Wolfram-Hubertus Zimmermann, Susann Boretius
Published 2021-05-01

CD8+-T Cells With Specificity for a Model Antigen in Cardiomyocytes Can Become Activated After Transverse Aortic Constriction but Do Not Accelerate Progression to Heart Failure

by Carina Gröschel, Carina Gröschel, André Sasse, Sebastian Monecke, Sebastian Monecke, Charlotte Röhrborn, Leslie Elsner, Michael Didié, Michael Didié, Michael Didié, Verena Reupke, Gertrude Bunt, Andrew H. Lichtman, Karl Toischer, Karl Toischer, Wolfram-Hubertus Zimmermann, Wolfram-Hubertus Zimmermann, Gerd Hasenfuß, Gerd Hasenfuß, Ralf Dressel, Ralf Dressel
Published 2018-11-01

Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids

by Maria-Patapia Zafeiriou, Guobin Bao, James Hudson, Rashi Halder, Alica Blenkle, Marie-Kristin Schreiber, Andre Fischer, Detlev Schild, Wolfram-Hubertus Zimmermann
Published 2020-07-01

Regeneration competent satellite cell niches in rat engineered skeletal muscle

by Malte Tiburcy, Alex Markov, Lena K. Kraemer, Peter Christalla, Margret Rave‐Fraenk, Henrike J. Fischer, Holger M. Reichardt, Wolfram‐Hubertus Zimmermann
Published 2019-12-01

RhoA Ambivalently Controls Prominent Myofibroblast Characteritics by Involving Distinct Signaling Routes.

by Aline Jatho, Svenja Hartmann, Naim Kittana, Felicitas Mügge, Christina M Wuertz, Malte Tiburcy, Wolfram-Hubertus Zimmermann, Dörthe M Katschinski, Susanne Lutz
Published 2015-01-01

Correction: Common MicroRNA Signatures in Cardiac Hypertrophic and Atrophic Remodeling Induced by Changes in Hemodynamic Load

by Ali El-Armouche, Alexander Peter Schwoerer, Christiane Neuber, Julius Emmons, Daniel Biermann, Thomas Christalla, Adam Grundhoff, Thomas Eschenhagen, Wolfram Hubertus Zimmermann, Heimo Ehmke
Published 2011-01-01

Common microRNA signatures in cardiac hypertrophic and atrophic remodeling induced by changes in hemodynamic load.

by Ali El-Armouche, Alexander Peter Schwoerer, Christiane Neuber, Julius Emons, Daniel Biermann, Thomas Christalla, Adam Grundhoff, Thomas Eschenhagen, Wolfram Hubertus Zimmermann, Heimo Ehmke
Published 2010-12-01

Correction: Common MicroRNA Signatures in Cardiac Hypertrophic and Atrophic Remodeling Induced by Changes in Hemodynamic Load.

by Ali El-Armouche, Alexander Peter Schwoerer, Christiane Neuber, Julius Emmons, Daniel Biermann, Thomas Christalla, Adam Grundhoff, Thomas Eschenhagen, Wolfram Hubertus Zimmermann, Heimo Ehmke
Published 2011-01-01

Human engineered heart tissue as a versatile tool in basic research and preclinical toxicology.

by Sebastian Schaaf, Aya Shibamiya, Marco Mewe, Alexandra Eder, Andrea Stöhr, Marc N Hirt, Thomas Rau, Wolfram-Hubertus Zimmermann, Lenard Conradi, Thomas Eschenhagen, Arne Hansen
Published 2011-01-01

Non-Human Primate iPSC Generation, Cultivation, and Cardiac Differentiation under Chemically Defined Conditions

by Michael Stauske, Ignacio Rodriguez Polo, Wadim Haas, Debbra Yasemin Knorr, Thomas Borchert, Katrin Streckfuss-Bömeke, Ralf Dressel, Iris Bartels, Malte Tiburcy, Wolfram-Hubertus Zimmermann, Rüdiger Behr
Published 2020-05-01

Lipopolysaccharides induced inflammatory responses and electrophysiological dysfunctions in human-induced pluripotent stem cell derived cardiomyocytes

by Gökhan Yücel, Zhihan Zhao, Ibrahim El-Battrawy, Huan Lan, Siegfried Lang, Xin Li, Fanis Buljubasic, Wolfram-Hubertus Zimmermann, Lukas Cyganek, Jochen Utikal, Ursula Ravens, Thomas Wieland, Martin Borggrefe, Xiao-Bo Zhou, Ibrahim Akin
Published 2017-06-01