Mechanistic modelling of tyrosine recombination reveals key parameters determining the performance of a CAR T cell switching circuit

by Jack E. Bowyer, Deboki Chakravarti, Wilson W. Wong, Declan G. Bates
Published 2020-02-01

Mechanistic modelling of a recombinase-based two-input temporal logic gate

by Jack E. Bowyer, Victoria Hsiao, Wilson W. Wong, Declan G. Bates
Published 2017-07-01

A mechanistic model of the BLADE platform predicts performance characteristics of 256 different synthetic DNA recombination circuits.

by Jack E Bowyer, Chloe Ding, Benjamin H Weinberg, Wilson W Wong, Declan G Bates
Published 2020-12-01

Targeted Chromatinization and Repression of HIV-1 Provirus Transcription with Repurposed CRISPR/Cas9

by Alex Olson, Binita Basukala, Seunghee Lee, Matthew Gagne, Wilson W. Wong, Andrew J. Henderson
Published 2020-10-01

Engineering advanced logic and distributed computing in human CAR immune cells

by Jang Hwan Cho, Atsushi Okuma, Katri Sofjan, Seunghee Lee, James J. Collins, Wilson W. Wong
Published 2021-02-01

Strength of T cell signaling regulates HIV-1 replication and establishment of latency.

by Matthew Gagne, Daniel Michaels, Gillian M Schiralli Lester, Suryaram Gummuluru, Wilson W Wong, Andrew J Henderson
Published 2019-05-01

Quantitative characterization of recombinase-based digitizer circuits enables predictable amplification of biological signals

by Katherine A. Kiwimagi, Justin H. Letendre, Benjamin H. Weinberg, Junmin Wang, Mingzhe Chen, Leandro Watanabe, Chris J. Myers, Jacob Beal, Wilson W. Wong, Ron Weiss
Published 2021-07-01

High-performance chemical- and light-inducible recombinases in mammalian cells and mice

by Benjamin H. Weinberg, Jang Hwan Cho, Yash Agarwal, N. T. Hang Pham, Leidy D. Caraballo, Maciej Walkosz, Charina Ortega, Micaela Trexler, Nathan Tague, Billy Law, William K. J. Benman, Justin Letendre, Jacob Beal, Wilson W. Wong
Published 2019-10-01