Biophysical attributes that affect CaMKII activation deduced with a novel spatial stochastic simulation approach.

by Ximing Li, William R Holmes
Published 2018-02-01

A comparison of computational models for eukaryotic cell shape and motility.

by William R Holmes, Leah Edelstein-Keshet
Published 2012-01-01

The Interplay between Wnt Mediated Expansion and Negative Regulation of Growth Promotes Robust Intestinal Crypt Structure and Homeostasis.

by Huijing Du, Qing Nie, William R Holmes
Published 2015-08-01

Modelling cell polarization driven by synthetic spatially graded Rac activation.

by William R Holmes, Benjamin Lin, Andre Levchenko, Leah Edelstein-Keshet
Published 2012-01-01

A mathematical model coupling polarity signaling to cell adhesion explains diverse cell migration patterns.

by William R Holmes, JinSeok Park, Andre Levchenko, Leah Edelstein-Keshet
Published 2017-05-01

Cell Sorting and Noise-Induced Cell Plasticity Coordinate to Sharpen Boundaries between Gene Expression Domains.

by Qixuan Wang, William R Holmes, Julian Sosnik, Thomas Schilling, Qing Nie
Published 2017-01-01

The impact of speed and bias on the cognitive processes of experts and novices in medical image decision-making

by Jennifer S. Trueblood, William R. Holmes, Adam C. Seegmiller, Jonathan Douds, Margaret Compton, Eszter Szentirmai, Megan Woodruff, Wenrui Huang, Charles Stratton, Quentin Eichbaum
Published 2018-07-01

Gene Expression Noise Enhances Robust Organization of the Early Mammalian Blastocyst.

by William R Holmes, Nabora Soledad Reyes de Mochel, Qixuan Wang, Huijing Du, Tao Peng, Michael Chiang, Olivier Cinquin, Ken Cho, Qing Nie
Published 2017-01-01