Leptin downregulates aggrecan through the p38-ADAMST pathway in human nucleus pulposus cells.

by Zheng Li, Xin Yu, Jinqian Liang, William Ka Kei Wu, Jun Yu, Jianxiong Shen
Published 2014-01-01

Vitamin A deficiency induces congenital spinal deformities in rats.

by Zheng Li, Jianxiong Shen, William Ka Kei Wu, Xiaojuan Wang, Jinqian Liang, Guixing Qiu, Jiaming Liu
Published 2012-01-01

Leptin Activates RhoA/ROCK Pathway to Induce Cytoskeleton Remodeling in Nucleus Pulposus Cells

by Zheng Li, Jinqian Liang, William Ka Kei Wu, Xin Yu, Jun Yu, Xisheng Weng, Jianxiong Shen
Published 2014-01-01

Leptin induces cyclin D1 expression and proliferation of human nucleus pulposus cells via JAK/STAT, PI3K/Akt and MEK/ERK pathways.

by Zheng Li, Jianxiong Shen, William Ka Kei Wu, Xin Yu, Jinqian Liang, Guixing Qiu, Jiaming Liu
Published 2012-01-01

wtest: an integrated R package for genetic epistasis testing

by Rui Sun, Xiaoxuan Xia, Ka Chun Chong, Benny Chung-Ying Zee, William Ka Kei Wu, Maggie Haitian Wang
Published 2019-12-01

Development of a predictive risk model for all-cause mortality in patients with diabetes in Hong Kong

by William Ka Kei Wu, Gary Tse, Ian Chi Kei Wong, Qingpeng Zhang, Jiandong Zhou, Sharen Lee, Keith Sai Kit Leung, Kamalan Jeevaratnam, Wing Tak Wong
Published 2021-08-01

Development of a multivariable prediction model for severe COVID-19 disease: a population-based study from Hong Kong

by Jiandong Zhou, Sharen Lee, Xiansong Wang, Yi Li, William Ka Kei Wu, Tong Liu, Zhidong Cao, Daniel Dajun Zeng, Keith Sai Kit Leung, Abraham Ka Chung Wai, Ian Chi Kei Wong, Bernard Man Yung Cheung, Qingpeng Zhang, Gary Tse
Published 2021-04-01

Bacteria pathogens drive host colonic epithelial cell promoter hypermethylation of tumor suppressor genes in colorectal cancer

by Xiaoxuan Xia, William Ka Kei Wu, Sunny Hei Wong, Dabin Liu, Thomas Ngai Yeung Kwong, Geicho Nakatsu, Pearlly S. Yan, Yu-Ming Chuang, Michael Wing-Yan Chan, Olabisi Oluwabukola Coker, Zigui Chen, Yun Kit Yeoh, Liuyang Zhao, Xiansong Wang, Wing Yin Cheng, Matthew Tak Vai Chan, Paul Kay Sheung Chan, Joseph Jao Yiu Sung, Maggie Haitian Wang, Jun Yu
Published 2020-07-01