Phase I hydroxylated metabolites of the K2 synthetic cannabinoid JWH-018 retain in vitro and in vivo cannabinoid 1 receptor affinity and activity.

by Lisa K Brents, Emily E Reichard, Sarah M Zimmerman, Jeffery H Moran, William E Fantegrossi, Paul L Prather
Published 2011-01-01

Identifying cytochrome P450s involved in oxidative metabolism of synthetic cannabinoid N‐(adamantan‐1‐yl)‐1‐(5‐fluoropentyl)‐1H‐indole‐3‐carboxamide (STS‐135)

by Sabrina Jones, Azure L. Yarbrough, William E. Fantegrossi, Paul L. Prather, John M. Bush, Anna Radominska‐Pandya, Ryoichi Fujiwara
Published 2020-02-01

Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics

by Anna O. Pinson, Dakota L. Pouncey, Mary A. Schleiff, William E. Fantegrossi, Paul L. Prather, Anna Radominska-Pandya, Gunnar Boysen, Grover P. Miller
Published 2020-10-01

Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ9-THC

by Rachel D. Hutchison, Benjamin M. Ford, Lirit N. Franks, Catheryn D. Wilson, Azure L. Yarbrough, Ryoichi Fujiwara, Mark K. Su, Denise Fernandez, Laura P. James, Jeffery H. Moran, Amy L. Patton, William E. Fantegrossi, Anna Radominska-Pandya, Paul L. Prather
Published 2018-09-01

In Vitro and In Vivo Characterization of the Alkaloid Nuciferine.

by Martilias S Farrell, John D McCorvy, Xi-Ping Huang, Daniel J Urban, Kate L White, Patrick M Giguere, Allison K Doak, Alison I Bernstein, Kristen A Stout, Su Mi Park, Ramona M Rodriguiz, Bradley W Gray, William S Hyatt, Andrew P Norwood, Kevin A Webster, Brenda M Gannon, Gary W Miller, Joseph H Porter, Brian K Shoichet, William E Fantegrossi, William C Wetsel, Bryan L Roth
Published 2016-01-01