The tandem repeats enabling reversible switching between the two phases of β-lactamase substrate spectrum.

by Hyojeong Yi, Han Song, Junghyun Hwang, Karan Kim, William C Nierman, Heenam Stanley Kim
Published 2014-09-01

Genomic and phenotypic characterization of Burkholderia isolates from the potable water system of the International Space Station.

by Aubrie O'Rourke, Michael D Lee, William C Nierman, R Craig Everroad, Chris L Dupont
Published 2020-01-01

Twelve positions in a β-lactamase that can expand its substrate spectrum with a single amino acid substitution.

by Hyojeong Yi, Kwang-Hwi Cho, Yun Sung Cho, Karan Kim, William C Nierman, Heenam Stanley Kim
Published 2012-01-01

The early stage of bacterial genome-reductive evolution in the host.

by Han Song, Junghyun Hwang, Hyojeong Yi, Ricky L Ulrich, Yan Yu, William C Nierman, Heenam Stanley Kim
Published 2010-05-01

Genome sequencing and analysis of Yersina pestis KIM D27, an avirulent strain exempt from select agent regulation.

by Liliana Losada, John J Varga, Jessica Hostetler, Diana Radune, Maria Kim, Scott Durkin, Olaf Schneewind, William C Nierman
Published 2011-04-01

Gene Expression Profiling and Identification of Resistance Genes to Aspergillus flavus Infection in Peanut through EST and Microarray Strategies

by Baozhu Guo, Natalie D. Fedorova, Xiaoping Chen, Chun-Hua Wan, Wei Wang, William C. Nierman, Deepak Bhatnagar, Jiujiang Yu
Published 2011-06-01

Longitudinal changes in the nasopharyngeal resistome of South African infants using shotgun metagenomic sequencing.

by Rendani I Manenzhe, Felix S Dube, Meredith Wright, Katie Lennard, Heather J Zar, Stephanie Mounaud, William C Nierman, Mark P Nicol, Clinton Moodley
Published 2020-01-01

Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeA.

by Robyn M Perrin, Natalie D Fedorova, Jin Woo Bok, Robert A Cramer, Jennifer R Wortman, H Stanley Kim, William C Nierman, Nancy P Keller
Published 2007-04-01

Whole genome comparison of Aspergillus flavus L-morphotype strain NRRL 3357 (type) and S-morphotype strain AF70.

by Matthew K Gilbert, Brian M Mack, Geromy G Moore, Darlene L Downey, Matthew D Lebar, Vinita Joardar, Liliana Losada, JiuJiang Yu, William C Nierman, Deepak Bhatnagar
Published 2018-01-01

The temporal dynamics of differential gene expression in Aspergillus fumigatus interacting with human immature dendritic cells in vitro.

by Charles O Morton, John J Varga, Anke Hornbach, Markus Mezger, Helga Sennefelder, Susanne Kneitz, Oliver Kurzai, Sven Krappmann, Hermann Einsele, William C Nierman, Thomas R Rogers, Juergen Loeffler
Published 2011-01-01

Characterization of clinically-attenuated Burkholderia mallei by whole genome sequencing: candidate strain for exclusion from Select Agent lists.

by Steven E Schutzer, Linda R K Schlater, Catherine M Ronning, David DeShazer, Benjamin J Luft, John J Dunn, Jacques Ravel, Claire M Fraser-Liggett, William C Nierman
Published 2008-04-01

Predicting antimicrobial mechanism-of-action from transcriptomes: A generalizable explainable artificial intelligence approach.

by Josh L Espinoza, Chris L Dupont, Aubrie O'Rourke, Sinem Beyhan, Pavel Morales, Amy Spoering, Kirsten J Meyer, Agnes P Chan, Yongwook Choi, William C Nierman, Kim Lewis, Karen E Nelson
Published 2021-03-01

Characterization of Pneumococcal Colonization Dynamics and Antimicrobial Resistance Using Shotgun Metagenomic Sequencing in Intensively Sampled South African Infants

by Rendani I. Manenzhe, Felix S. Dube, Felix S. Dube, Meredith Wright, Katie Lennard, Stephanie Mounaud, Stephanie W. Lo, Heather J. Zar, William C. Nierman, Mark P. Nicol, Mark P. Nicol, Clinton Moodley, Clinton Moodley
Published 2020-09-01

Genetic Analysis Using an Isogenic Mating Pair of Aspergillus fumigatus Identifies Azole Resistance Genes and Lack of MAT Locus's Role in Virulence.

by Liliana Losada, Janyce A Sugui, Michael A Eckhaus, Yun C Chang, Stephanie Mounaud, Abigail Figat, Vinita Joardar, Suman B Pakala, Suchitra Pakala, Pratap Venepally, Natalie Fedorova, William C Nierman, Kyung J Kwon-Chung
Published 2015-04-01

Sub-telomere directed gene expression during initiation of invasive aspergillosis.

by Andrew McDonagh, Natalie D Fedorova, Jonathan Crabtree, Yan Yu, Stanley Kim, Dan Chen, Omar Loss, Timothy Cairns, Gustavo Goldman, Darius Armstrong-James, Ken Haynes, Hubertus Haas, Markus Schrettl, Gregory May, William C Nierman, Elaine Bignell
Published 2008-09-01

HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus.

by Xizhi Feng, Karthik Krishnan, Daryl L Richie, Vishukumar Aimanianda, Lukas Hartl, Nora Grahl, Margaret V Powers-Fletcher, Minlu Zhang, Kevin K Fuller, William C Nierman, Long Jason Lu, Jean-Paul Latgé, Laura Woollett, Simon L Newman, Robert A Cramer, Judith C Rhodes, David S Askew
Published 2011-10-01

Clonality despite sex: the evolution of host-associated sexual neighborhoods in the pathogenic fungus Penicillium marneffei.

by Daniel A Henk, Revital Shahar-Golan, Khuraijam Ranjana Devi, Kylie J Boyce, Nengyong Zhan, Natalie D Fedorova, William C Nierman, Po-Ren Hsueh, Kwok-Yung Yuen, Tran P M Sieu, Nguyen Van Kinh, Heiman Wertheim, Stephen G Baker, Jeremy N Day, Nongnuch Vanittanakom, Elaine M Bignell, Alex Andrianopoulos, Matthew C Fisher
Published 2012-01-01

Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus

by Philipp eWiemann, Beatrix E. Lechner, Joshua A. Baccile, Joshua A. Baccile, Thomas A. Velk, Wen-Bing eYin, Wen-Bing eYin, Jin Woo eBok, Liliana eLosada, Suman ePakala, William C. Nierman, Frank C. Schroeder, Frank C. Schroeder, Hubertus eHaas, Nancy P. Keller, Nancy P. Keller
Published 2014-10-01

Strain Level Streptococcus Colonization Patterns during the First Year of Life

by Meredith S. Wright, Jamison McCorrison, Andres M. Gomez, Erin Beck, Derek Harkins, Jyoti Shankar, Stephanie Mounaud, Edelwisa Segubre-Mercado, Aileen May R. Mojica, Brian Bacay, Susan A. Nzenze, Sheila Z. M. Kimaro, Peter Adrian, Keith P. Klugman, Marilla G. Lucero, Karen E. Nelson, Shabir Madhi, Granger G. Sutton, William C. Nierman, Liliana Losada
Published 2017-09-01

The pH-responsive PacC transcription factor of Aspergillus fumigatus governs epithelial entry and tissue invasion during pulmonary aspergillosis.

by Margherita Bertuzzi, Markus Schrettl, Laura Alcazar-Fuoli, Timothy C Cairns, Alberto Muñoz, Louise A Walker, Susanne Herbst, Maryam Safari, Angela M Cheverton, Dan Chen, Hong Liu, Shinobu Saijo, Natalie D Fedorova, Darius Armstrong-James, Carol A Munro, Nick D Read, Scott G Filler, Eduardo A Espeso, William C Nierman, Hubertus Haas, Elaine M Bignell
Published 2014-10-01