Deducing protein function by forensic integrative cell biology.

by William C Earnshaw
Published 2013-12-01

The dawn of Aurora kinase research: from fly genetics to the clinic.

by Mar eCarmena, William C. Earnshaw, David eGlover
Published 2015-11-01

Polo kinase regulates the localization and activity of the chromosomal passenger complex in meiosis and mitosis in Drosophila melanogaster

by Mar Carmena, Miguel Ortiz Lombardia, Hiromi Ogawa, William C. Earnshaw
Published 2014-01-01

Targeting the INCENP IN-box–Aurora B interaction to inhibit CPC activity in vivo

by Florence H. Gohard, Daniel J. St-Cyr, Mike Tyers, William C. Earnshaw
Published 2014-01-01

The intrinsically disorderly story of Ki-67

by Lucy Remnant, Natalia Y. Kochanova, Caitlin Reid, Fernanda Cisneros-Soberanis, William C. Earnshaw
Published 2021-08-01

Common Fragile Sites Are Characterized by Faulty Condensin Loading after Replication Stress

by Lora Boteva, Ryu-Suke Nozawa, Catherine Naughton, Kumiko Samejima, William C. Earnshaw, Nick Gilbert
Published 2020-09-01

Mitotic post-translational modifications of histones promote chromatin compaction in vitro

by Alisa Zhiteneva, Juan Jose Bonfiglio, Alexandr Makarov, Thomas Colby, Paola Vagnarelli, Eric C. Schirmer, Ivan Matic, William C. Earnshaw
Published 2017-01-01

Three-dimensional topology of the SMC2/SMC4 subcomplex from chicken condensin I revealed by cross-linking and molecular modelling

by Helena Barysz, Ji Hun Kim, Zhuo Angel Chen, Damien F. Hudson, Juri Rappsilber, Dietlind L. Gerloff, William C. Earnshaw
Published 2015-01-01

Epigenetic engineering reveals a balance between histone modifications and transcription in kinetochore maintenance

by Oscar Molina, Giulia Vargiu, Maria Alba Abad, Alisa Zhiteneva, A. Arockia Jeyaprakash, Hiroshi Masumoto, Natalay Kouprina, Vladimir Larionov, William C. Earnshaw
Published 2016-11-01

Reed-Sternberg cells form by abscission failure in the presence of functional Aurora B kinase.

by Ana Xavier de Carvalho, Helder Maiato, André F Maia, Susana A Ribeiro, Patrícia Pontes, Wendy Bickmore, William C Earnshaw, Clara Sambade
Published 2015-01-01

Auxin/AID versus conventional knockouts: distinguishing the roles of CENP-T/W in mitotic kinetochore assembly and stability

by Laura Wood, Daniel G. Booth, Giulia Vargiu, Shinya Ohta, Flavia deLima Alves, Kumiko Samejima, Tatsuo Fukagawa, Juri Rappsilber, William C. Earnshaw
Published 2016-01-01

The chromosomal passenger complex activates Polo kinase at centromeres.

by Mar Carmena, Xavier Pinson, Melpi Platani, Zeina Salloum, Zhenjie Xu, Anthony Clark, Fiona Macisaac, Hiromi Ogawa, Ulrike Eggert, David M Glover, Vincent Archambault, William C Earnshaw
Published 2012-01-01

Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery

by Daniel G Booth, Masatoshi Takagi, Luis Sanchez-Pulido, Elizabeth Petfalski, Giulia Vargiu, Kumiko Samejima, Naoko Imamoto, Chris P Ponting, David Tollervey, William C Earnshaw, Paola Vagnarelli
Published 2014-05-01

Correction: The Chromosomal Passenger Complex Activates Polo Kinase at Centromeres.

by Mar Carmena, Xavier Pinson, Melpi Platani, Zeina Salloum, Zhenjie Xu, Anthony Clark, Fiona MacIsaac, Hiromi Ogawa, Ulrike Eggert, David M. Glover, Vincent Archambault, William C. Earnshaw
Published 2012-02-01

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

by Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond, Su Chu, Alan R. Healy, Gergana Popova, Andrés Pastor Fernández, Tanzina Mollick, Suhas Darekar, Saikiran K. Sedimbi, Marta Nekulova, Marijke C. C. Sachweh, Johanna Campbell, Maureen Higgins, Chloe Tuck, Mihaela Popa, Mireia Mayoral Safont, Pascal Gelebart, Zinayida Fandalyuk, Alastair M. Thompson, Richard Svensson, Anna-Lena Gustavsson, Lars Johansson, Katarina Färnegårdh, Ulrika Yngve, Aljona Saleh, Martin Haraldsson, Agathe C. A. D’Hollander, Marcela Franco, Yan Zhao, Maria Håkansson, Björn Walse, Karin Larsson, Emma M. Peat, Vicent Pelechano, John Lunec, Borivoj Vojtesek, Mar Carmena, William C. Earnshaw, Anna R. McCarthy, Nicholas J. Westwood, Marie Arsenian-Henriksson, David P. Lane, Ravi Bhatia, Emmet McCormack, Sonia Laín
Published 2018-03-01

Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

by Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond, Su Chu, Alan R. Healy, Gergana Popova, Andrés Pastor Fernández, Tanzina Mollick, Suhas Darekar, Saikiran K. Sedimbi, Marta Nekulova, Marijke C. C. Sachweh, Johanna Campbell, Maureen Higgins, Chloe Tuck, Mihaela Popa, Mireia Mayoral Safont, Pascal Gelebart, Zinayida Fandalyuk, Alastair M. Thompson, Richard Svensson, Anna-Lena Gustavsson, Lars Johansson, Katarina Färnegårdh, Ulrika Yngve, Aljona Saleh, Martin Haraldsson, Agathe C. A. D’Hollander, Marcela Franco, Yan Zhao, Maria Håkansson, Björn Walse, Karin Larsson, Emma M. Peat, Vicent Pelechano, John Lunec, Borivoj Vojtesek, Mar Carmena, William C. Earnshaw, Anna R. McCarthy, Nicholas J. Westwood, Marie Arsenian-Henriksson, David P. Lane, Ravi Bhatia, Emmet McCormack, Sonia Laín
Published 2018-05-01