Regulatory and evolutionary signatures of sex-biased genes on both the X chromosome and the autosomes

by Jiangshan J. Shen, Ting-You Wang, Wanling Yang
Published 2017-11-01

A systems view of the differences between APOE ε4 carriers and non-carriers in Alzheimer’s disease

by Shan Jiang, Ling Tang, Na Zhao, Wanling Yang, Yu Qiu, Hong-zhuan Chen
Published 2016-07-01

Application of Weighted Gene Coexpression Network Analysis to Identify Key Modules and Hub Genes in Systemic Juvenile Idiopathic Arthritis

by Mi Zhou, Ruru Guo, Yong-Fei Wang, Wanling Yang, Rongxiu Li, Liangjing Lu
Published 2021-01-01

Sex-Interacting mRNA- and miRNA-eQTLs and Their Implications in Gene Expression Regulation and Disease

by Jiangshan J. Shen, Jiangshan J. Shen, Jiangshan J. Shen, Yong-Fei Wang, Wanling Yang
Published 2019-04-01

Systemic Lupus Erythematosus Patients Exhibit Reduced Expression of CLEC16A Isoforms in Peripheral Leukocytes

by Rachel C. Y. Tam, Alfred L. H. Lee, Wanling Yang, Chak Sing Lau, Vera S. F. Chan
Published 2015-06-01

Connection between the Gut Microbiota of Largemouth Bass (<i>Micropterus salmoides</i>) and Microbiota of the Pond Culture Environment

by Qianfu Liu, Zini Lai, Yuan Gao, Chao Wang, Yanyi Zeng, Erchun Liu, Yongzhan Mai, Wanling Yang, Haiyan Li
Published 2021-08-01

LncRNA PVT1 triggers Cyto-protective autophagy and promotes pancreatic ductal adenocarcinoma development via the miR-20a-5p/ULK1 Axis

by Fengting Huang, Wenying Chen, Juanfei Peng, Yuanhua Li, Yanyan Zhuang, Zhe Zhu, Chunkui Shao, Wanling Yang, Herui Yao, Shineng Zhang
Published 2018-07-01

Predicting mendelian disease-causing non-synonymous single nucleotide variants in exome sequencing studies.

by Miao-Xin Li, Johnny S H Kwan, Su-Ying Bao, Wanling Yang, Shu-Leong Ho, Yong-Qiang Song, Pak C Sham
Published 2013-01-01

Revisit of Optimal Donor Number Estimation in the Hong Kong Bone Marrow Donor Registry

by Jenny Chung Yee Ho, Stephen Kwok Fan Cheung, Zhongyi Lui, Ivan Wing Hong Tang, Wanling Yang, Patrick Ip, Cheuk Kwong Lee, Derek Middleton, Janette Siu Yin Kwok
Published 2021-04-01

A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus.

by Xiaobing Luo, Wanling Yang, Dong-Qing Ye, Huijuan Cui, Yan Zhang, Nattiya Hirankarn, Xiaoxia Qian, Yuanjia Tang, Yu Lung Lau, Niek de Vries, Paul Peter Tak, Betty P Tsao, Nan Shen
Published 2011-06-01

Application of Flow Cytometry in the Diagnostics Pipeline of Primary Immunodeficiencies Underlying Disseminated Talaromyces marneffei Infection in HIV-Negative Children

by Pamela P. Lee, Pamela P. Lee, Mongkol Lao-araya, Jing Yang, Koon-Wing Chan, Haiyan Ma, Lim-Cho Pei, Lin Kui, Huawei Mao, Wanling Yang, Xiaodong Zhao, Muthita Trakultivakorn, Yu-Lung Lau, Yu-Lung Lau
Published 2019-09-01

Meta-analysis of GWAS on both Chinese and European populations identifies GPR173 as a novel X chromosome susceptibility gene for SLE

by Huoru Zhang, Yan Zhang, Yong-Fei Wang, David Morris, Nattiya Hirankarn, Yujun Sheng, Jiangshan Shen, Hai-Feng Pan, Jing Yang, Sen Yang, Yong Cui, Dong-Qing Ye, Timothy J. Vyse, Xuejun Zhang, Yu Lung Lau, Wanling Yang
Published 2018-05-01

Independent Replication on Genome-Wide Association Study Signals Identifies IRF3 as a Novel Locus for Systemic Lupus Erythematosus

by Feixia Zhang, Yong-Fei Wang, Yong-Fei Wang, Yan Zhang, Zhiming Lin, Yujie Cao, Huoru Zhang, Zhong-Yi Liu, David L. Morris, Yujun Sheng, Yong Cui, Xuejun Zhang, Timothy J. Vyse, Yu Lung Lau, Wanling Yang, Yanhui Chen
Published 2020-07-01

Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism

by Kit San Yeung, Winnie Wan Yee Tso, Janice Jing Kun Ip, Christopher Chun Yu Mak, Gordon Ka Chun Leung, Mandy Ho Yin Tsang, Dingge Ying, Steven Lim Cho Pei, So Lun Lee, Wanling Yang, Brian Hon-Yin Chung
Published 2017-12-01

The clinical impact of chromosomal microarray on paediatric care in Hong Kong.

by Victoria Q Tao, Kelvin Y K Chan, Yoyo W Y Chu, Gary T K Mok, Tiong Y Tan, Wanling Yang, So Lun Lee, Wing Fai Tang, Winnie W Y Tso, Elizabeth T Lau, Anita S Y Kan, Mary H Tang, Yu-Lung Lau, Brian H Y Chung
Published 2014-01-01

Genome-Wide DNA Methylation Analysis of Chinese Patients with Systemic Lupus Erythematosus Identified Hypomethylation in Genes Related to the Type I Interferon Pathway.

by Kit San Yeung, Brian Hon-Yin Chung, Sanaa Choufani, Mo Yin Mok, Wai Lap Wong, Christopher Chun Yu Mak, Wanling Yang, Pamela Pui Wah Lee, Wilfred Hing Sang Wong, Yi-An Chen, Daria Grafodatskaya, Raymond Woon Sing Wong, Chak Sing Lau, Daniel Tak Mao Chan, Rosanna Weksberg, Yu-Lung Lau
Published 2017-01-01

Identifying the genetic causes for prenatally diagnosed structural congenital anomalies (SCAs) by whole-exome sequencing (WES)

by Gordon K C Leung, Christopher C Y Mak, Jasmine L F Fung, Wilfred H S Wong, Mandy H Y Tsang, Mullin H C Yu, Steven L C Pei, K S Yeung, Gary T K Mok, C P Lee, Amelia P W Hui, Mary H Y Tang, Kelvin Y K Chan, Anthony P Y Liu, Wanling Yang, P C Sham, Anita S Y Kan, Brian H Y Chung
Published 2018-10-01

Actionable pharmacogenetic variants in Hong Kong Chinese exome sequencing data and projected prescription impact in the Hong Kong population.

by Mullin Ho Chung Yu, Marcus Chun Yin Chan, Claudia Ching Yan Chung, Andrew Wang Tat Li, Chara Yin Wa Yip, Christopher Chun Yu Mak, Jeffrey Fong Ting Chau, Mianne Lee, Jasmine Lee Fong Fung, Mandy Ho Yin Tsang, Joshua Chun Ki Chan, Wilfred Hing Sang Wong, Jing Yang, William Chun Ming Chui, Patrick Ho Yu Chung, Wanling Yang, So Lun Lee, Godfrey Chi Fung Chan, Paul Kwong Hang Tam, Yu Lung Lau, Clara Sze Man Tang, Kit San Yeung, Brian Hon Yin Chung
Published 2021-02-01

Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups

by Yong-Fei Wang, Yan Zhang, Zhiming Lin, Huoru Zhang, Ting-You Wang, Yujie Cao, David L. Morris, Yujun Sheng, Xianyong Yin, Shi-Long Zhong, Xiaoqiong Gu, Yao Lei, Jing He, Qi Wu, Jiangshan Jane Shen, Jing Yang, Tai-Hing Lam, Jia-Huang Lin, Zhi-Ming Mai, Mengbiao Guo, Yuanjia Tang, Yanhui Chen, Qin Song, Bo Ban, Chi Chiu Mok, Yong Cui, Liangjing Lu, Nan Shen, Pak C. Sham, Chak Sing Lau, David K. Smith, Timothy J. Vyse, Xuejun Zhang, Yu Lung Lau, Wanling Yang
Published 2021-02-01

Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus.

by Wanling Yang, Nan Shen, Dong-Qing Ye, Qiji Liu, Yan Zhang, Xiao-Xia Qian, Nattiya Hirankarn, Dingge Ying, Hai-Feng Pan, Hai-Feng Pan, Chi Chiu Mok, Tak Mao Chan, Raymond Woon Sing Wong, Ka Wing Lee, Mo Yin Mok, Sik Nin Wong, Alexander Moon Ho Leung, Xiang-Pei Li, Yingyos Avihingsanon, Chun-Ming Wong, Tsz Leung Lee, Marco Hok Kung Ho, Pamela Pui Wah Lee, Yuk Kwan Chang, Philip H Li, Ruo-Jie Li, Lu Zhang, Wilfred Hing Sang Wong, Irene Oi Lin Ng, Chak Sing Lau, Pak Chung Sham, Yu Lung Lau, Asian Lupus Genetics Consortium
Published 2010-02-01