SHP-2 in Lymphocytes' Cytokine and Inhibitory Receptor Signaling

by Charlène Niogret, Walter Birchmeier, Greta Guarda
Published 2019-10-01

Beneficial effect of voluntary physical exercise in Plakophilin2 transgenic mice.

by Karin P Hammer, Julian Mustroph, Teresa Stauber, Walter Birchmeier, Stefan Wagner, Lars S Maier
Published 2021-01-01

Gab1 and Mapk Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence

by Özlem Akilli Öztürk, Hubert Pakula, Jolanta Chmielowiec, Jingjing Qi, Simone Stein, Linxiang Lan, Yoshiteru Sasaki, Klaus Rajewsky, Walter Birchmeier
Published 2015-10-01

Tracing tumorigenesis in a solid tumor model at single-cell resolution

by Samantha D. Praktiknjo, Benedikt Obermayer, Qionghua Zhu, Liang Fang, Haiyue Liu, Hazel Quinn, Marlon Stoeckius, Christine Kocks, Walter Birchmeier, Nikolaus Rajewsky
Published 2020-02-01

Combined Wnt/β-Catenin, Met, and CXCL12/CXCR4 Signals Characterize Basal Breast Cancer and Predict Disease Outcome

by Jane D. Holland, Balázs Györffy, Regina Vogel, Klaus Eckert, Giovanni Valenti, Liang Fang, Philipp Lohneis, Sefer Elezkurtaj, Ulrike Ziebold, Walter Birchmeier
Published 2013-12-01

Shp-2 Is Dispensable for Establishing T Cell Exhaustion and for PD-1 Signaling In Vivo

by Giorgia Rota, Charlène Niogret, Anh Thu Dang, Cristina Ramon Barros, Nicolas Pierre Fonta, Francesca Alfei, Leonor Morgado, Dietmar Zehn, Walter Birchmeier, Eric Vivier, Greta Guarda
Published 2018-04-01

Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients

by Annika Fendler, Daniel Bauer, Jonas Busch, Klaus Jung, Annika Wulf-Goldenberg, Severine Kunz, Kun Song, Adam Myszczyszyn, Sefer Elezkurtaj, Bettina Erguen, Simone Jung, Wei Chen, Walter Birchmeier
Published 2020-02-01

The Wnt-Driven Mll1 Epigenome Regulates Salivary Gland and Head and Neck Cancer

by Qionghua Zhu, Liang Fang, Julian Heuberger, Andrea Kranz, Jörg Schipper, Kathrin Scheckenbach, Ramon Oliveira Vidal, Daniele Yumi Sunaga-Franze, Marion Müller, Annika Wulf-Goldenberg, Sascha Sauer, Walter Birchmeier
Published 2019-01-01

Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells

by Charlène Niogret, S. M. Shahjahan Miah, Giorgia Rota, Nicolas P. Fonta, Haiping Wang, Werner Held, Walter Birchmeier, Veronica Sexl, Wentian Yang, Eric Vivier, Ping-Chih Ho, Laurent Brossay, Greta Guarda
Published 2019-03-01

The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness

by Johanna Grinat, Julian Heuberger, Ramon Oliveira Vidal, Neha Goveas, Frauke Kosel, Antoni Berenguer-Llergo, Andrea Kranz, Annika Wulf-Goldenberg, Diana Behrens, Bálint Melcher, Sascha Sauer, Michael Vieth, Eduard Batlle, A. Francis Stewart, Walter Birchmeier
Published 2020-12-01

RNF4-Dependent Oncogene Activation by Protein Stabilization

by Jane J. Thomas, Mona Abed, Julian Heuberger, Rostislav Novak, Yaniv Zohar, Angela P. Beltran Lopez, Julie S. Trausch-Azar, Ma. Xenia G. Ilagan, David Benhamou, Gunnar Dittmar, Raphael Kopan, Walter Birchmeier, Alan L. Schwartz, Amir Orian
Published 2016-09-01

Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain

by Danielle M. DiCara, Dimitri Y. Chirgadze, Anthony R. Pope, Aneesh Karatt-Vellatt, Anja Winter, Peter Slavny, Joop van den Heuvel, Kothai Parthiban, Jane Holland, Len C. Packman, Georgia Mavria, Jens Hoffmann, Walter Birchmeier, Ermanno Gherardi, John McCafferty
Published 2017-08-01

The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis

by Ariella Zehender, Jingang Huang, Andrea-Hermina Györfi, Alexandru-Emil Matei, Thuong Trinh-Minh, Xiaohan Xu, Yi-Nan Li, Chih-Wei Chen, Jianping Lin, Clara Dees, Christian Beyer, Kolja Gelse, Zhong-Yin Zhang, Christina Bergmann, Andreas Ramming, Walter Birchmeier, Oliver Distler, Georg Schett, Jörg H. W. Distler
Published 2018-08-01

Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells.

by Karsten Jürchott, Ralf-Jürgen Kuban, Till Krech, Nils Blüthgen, Ulrike Stein, Wolfgang Walther, Christian Friese, Szymon M Kiełbasa, Ute Ungethüm, Per Lund, Thomas Knösel, Wolfgang Kemmner, Markus Morkel, Johannes Fritzmann, Peter M Schlag, Walter Birchmeier, Tammo Krueger, Silke Sperling, Christine Sers, Hans-Dieter Royer, Hanspeter Herzel, Reinhold Schäfer
Published 2010-12-01

Oxidized LDL‐dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy

by Elena Sommariva, Ilaria Stadiotti, Michela Casella, Valentina Catto, Antonio Dello Russo, Corrado Carbucicchio, Lorenzo Arnaboldi, Simona De Metrio, Giuseppina Milano, Alessandro Scopece, Manuel Casaburo, Daniele Andreini, Saima Mushtaq, Edoardo Conte, Mattia Chiesa, Walter Birchmeier, Elisa Cogliati, Adolfo Paolin, Eva König, Viviana Meraviglia, Monica De Musso, Chiara Volani, Giada Cattelan, Werner Rauhe, Linda Turnu, Benedetta Porro, Matteo Pedrazzini, Marina Camera, Alberto Corsini, Claudio Tondo, Alessandra Rossini, Giulio Pompilio
Published 2021-09-01