613 HER2-XPAT, a novel protease-activatable prodrug T cell engager (TCE), with potent T-cell activation and efficacy in solid tumors and large predicted safety margins in non-human...

by Fiore Cattaruzza, Ayesha Nazeer, Zachary Lange, Caitlin Koski, Mikhail Hammond, Trang Dao-Pick, Angela Henkensiefken, Mika Derynck, Volker Schellenberger, Bryan Irving
Published 2020-11-01

GLP2-2G-XTEN: a pharmaceutical protein with improved serum half-life and efficacy in a rat Crohn's disease model.

by Susan E Alters, Bryant McLaughlin, Benjamin Spink, Tigran Lachinyan, Chia-wei Wang, Vladimir Podust, Volker Schellenberger, Willem P C Stemmer
Published 2012-01-01

GLP2-2G-XTEN: a pharmaceutical protein with improved serum half-life and efficacy in a rat Crohn's. PLoS One. 2012; 7(11): e50630.

by Susan E Alters, Bryant McLaughlin, Benjamin Spink, Tigran Lachinyan, Chia-Wei Wang, Vladimir Podust, Volker Schellenberger, Willem P C Stemmer
Published 2013-01-01

Gcg-XTEN: an improved glucagon capable of preventing hypoglycemia without increasing baseline blood glucose.

by Nathan C Geething, Wayne To, Benjamin J Spink, Michael D Scholle, Chia-wei Wang, Yong Yin, Yi Yao, Volker Schellenberger, Jeffrey L Cleland, Willem P C Stemmer, Joshua Silverman
Published 2010-04-01