Substituted N-Benzylpyrazine-2-carboxamides: Synthesis and Biological Evaluation

by Katarína Kráľová, Pavla Paterová, Matúš Peško, Vladimír Kubíček, Martin Doležal, Drahomíra Eibinová, Barbora Servusová
Published 2012-11-01

Direct Amination of Nitroquinoline Derivatives via Nucleophilic Displacement of Aromatic Hydrogen

by Jakub Wantulok, Daniel Swoboda, Jacek E. Nycz, Maria Książek, Joachim Kusz, Jan Grzegorz Małecki, Vladimír Kubíček
Published 2021-03-01

Carbonyl Reduction of Flubendazole in the Human Liver: Strict Stereospecificity, Sex Difference, Low Risk of Drug Interactions

by Vladimír Kubíček, Lenka Skálová, Adam Skarka, Věra Králová, Jana Holubová, Jana Štěpánková, Zdeněk Šubrt, Zdeněk Šubrt, Barbora Szotáková
Published 2019-05-01

New Potentially Active Pyrazinamide Derivatives Synthesized Under Microwave Conditions

by Ondrej Jandourek, Martin Dolezal, Jiri Kunes, Vladimir Kubicek, Pavla Paterova, Matus Pesko, Vladimir Buchta, Katarina Kralova, Jan Zitko
Published 2014-07-01

Synthesis of Novel Pyrazinamide Derivatives Based on 3-Chloropyrazine-2-carboxamide and Their Antimicrobial Evaluation

by Ondrej Jandourek, Marek Tauchman, Pavla Paterova, Klara Konecna, Lucie Navratilova, Vladimir Kubicek, Ondrej Holas, Jan Zitko, Martin Dolezal
Published 2017-02-01

N-Substituted 5-Amino-6-methylpyrazine-2,3-dicarbonitriles: Microwave-Assisted Synthesis and Biological Properties

by Ondrej Jandourek, Martin Dolezal, Pavla Paterova, Vladimir Kubicek, Matus Pesko, Jiri Kunes, Aidan Coffey, Jiahui Guo, Katarina Kralova
Published 2014-01-01

Derivatives of 3-Aminopyrazine-2-carboxamides: Synthesis, Antimicrobial Evaluation, and in Vitro Cytotoxicity

by Ghada Bouz, Lucia Semelková, Ondřej Janďourek, Klára Konečná, Pavla Paterová, Lucie Navrátilová, Vladimír Kubíček, Jiří Kuneš, Martin Doležal, Jan Zitko
Published 2019-03-01

Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions

by Alena Špičáková, Barbora Szotáková, Diana Dimunová, Zuzana Myslivečková, Vladimír Kubíček, Martin Ambrož, Kateřina Lněničková, Kristýna Krasulová, Pavel Anzenbacher, Lenka Skálová
Published 2017-03-01

Synthesis, Antimycobacterial Activity and In Vitro Cytotoxicity of 5-Chloro-N-phenylpyrazine-2-carboxamides

by Jan Zitko, Barbora Servusová, Pavla Paterová, Jana Mandíková, Vladimír Kubíček, Radim Kučera, Veronika Hrabcová, Jiří Kuneš, Ondřej Soukup, Martin Doležal
Published 2013-12-01

Synthesis and Biological Evaluation of N-Alkyl-3-(alkylamino)-pyrazine-2-carboxamides

by Lucia Semelkova, Klara Konecna, Pavla Paterova, Vladimir Kubicek, Jiri Kunes, Lucie Novakova, Jan Marek, Lieve Naesens, Matus Pesko, Katarina Kralova, Martin Dolezal, Jan Zitko
Published 2015-05-01

<i>N</i>-Pyrazinoyl Substituted Amino Acids as Potential Antimycobacterial Agents—the Synthesis and Biological Evaluation of Enantiomers

by Martin Juhás, Lucie Kučerová, Ondřej Horáček, Ondřej Janďourek, Vladimír Kubíček, Klára Konečná, Radim Kučera, Pavel Bárta, Jiří Janoušek, Pavla Paterová, Jiří Kuneš, Martin Doležal, Jan Zitko
Published 2020-03-01

Substituted <i>N</i>-(Pyrazin-2-yl)benzenesulfonamides; Synthesis, Anti-Infective Evaluation, Cytotoxicity, and In Silico Studies

by Ghada Bouz, Martin Juhás, Lluis Pausas Otero, Cristina Paredes de la Red, Ondřej Janďourek, Klára Konečná, Pavla Paterová, Vladimír Kubíček, Jiří Janoušek, Martin Doležal, Jan Zitko
Published 2019-12-01