Targeting of AKT/ERK/CTNNB1 by DAW22 as a potential therapeutic compound for malignant peripheral nerve sheath tumor

by Xiao‐Xiao Li, Shi‐Jie Zhang, Amy P. Chiu, Lilian H. Lo, Jian Huang, Dewi K. Rowlands, Jinhui Wang, Vincent W. Keng
Published 2018-09-01

Conditional Inactivation of Nf1 and Pten in Schwann Cells Results in Abnormal Neuromuscular Junction Maturation

by Xiao-Xiao Li, Shi-Jie Zhang, Amy P. Chiu, Lilian H. Lo, Jeffery C. To, He-Ning Cui, Dewi K. Rowlands, Vincent W. Keng
Published 2019-01-01

Sodium tanshinone IIA sulfonate ameliorates hepatic steatosis by inhibiting lipogenesis and inflammation

by Xiao-Xiao Li, Xin-Yi Lu, Shi-Jie Zhang, Amy P. Chiu, Lilian H. Lo, David A. Largaespada, Qu-Bo Chen, Vincent W. Keng
Published 2019-03-01

Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST

by Vincent W. Keng, Adrienne L. Watson, Eric P. Rahrmann, Hua Li, Barbara R. Tschida, Branden S. Moriarity, Kwangmin Choi, Tilat A. Rizvi, Margaret H. Collins, Margaret R. Wallace, Nancy Ratner, David A. Largaespada
Published 2012-01-01

Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel driver of hepatocarcinogenesis.

by Jesse D Riordan, Vincent W Keng, Barbara R Tschida, Todd E Scheetz, Jason B Bell, Kelly M Podetz-Pedersen, Catherine D Moser, Neal G Copeland, Nancy A Jenkins, Lewis R Roberts, David A Largaespada, Adam J Dupuy
Published 2013-04-01

ZBTB20 regulates WNT/CTNNB1 signalling pathway by suppressing PPARG during hepatocellular carcinoma tumourigenesis

by Jeffrey C. To, Amy P. Chiu, Barbara R. Tschida, Lilian H. Lo, Cynthia H. Chiu, Xiao-Xiao Li, Timothy P. Kuka, Michael A. Linden, Khalid Amin, Wing-Cheung Chan, Jason B. Bell, Branden S. Moriarity, David A. Largaespada, Vincent W. Keng
Published 2021-04-01

R‐spondin 2 Drives Liver Tumor Development in a Yes‐Associated Protein‐Dependent Manner

by Caitlin B. Conboy, Germán L. Vélez‐Reyes, Barbara R. Tschida, Hsiangyu Hu, Gabriel Kaufmann, Nicholas Koes, Bryant Keller, Clara Alsinet, Helena Cornellà, Roser Pinyol, Juan E. Abrahante, Nuri A. Temiz, Michael A. Linden, Khalid Amin, Timothy P. Kuka, Vincent W. Keng, Josep M. Llovet, Timothy K. Starr, David A. Largaespada
Published 2019-11-01

Insertional Mutagenesis Identifies a STAT3/Arid1b/β-catenin Pathway Driving Neurofibroma Initiation

by Jianqiang Wu, Vincent W. Keng, Deanna M. Patmore, Jed J. Kendall, Ami V. Patel, Edwin Jousma, Walter J. Jessen, Kwangmin Choi, Barbara R. Tschida, Kevin A.T. Silverstein, Danhua Fan, Eric B. Schwartz, James R. Fuchs, Yuanshu Zou, Mi-Ok Kim, Eva Dombi, David E. Levy, Gang Huang, Jose A. Cancelas, Anat O. Stemmer-Rachamimov, Robert J. Spinner, David A. Largaespada, Nancy Ratner
Published 2016-03-01