Infection-Induced Systemic Inflammation Is a Potential Driver of Alzheimer's Disease Progression

by Vijayasree V. Giridharan, Faisal Masud, Fabricia Petronilho, Felipe Dal-Pizzol, Tatiana Barichello, Tatiana Barichello, Tatiana Barichello
Published 2019-05-01

Schisandrin B prevents doxorubicin induced cardiac dysfunction by modulation of DNA damage, oxidative stress and inflammation through inhibition of MAPK/p53 signaling.

by Rajarajan A Thandavarayan, Vijayasree V Giridharan, Somasundaram Arumugam, Kenji Suzuki, Kam Ming Ko, Prasanna Krishnamurthy, Kenichi Watanabe, Tetsuya Konishi
Published 2015-01-01

Neuroinflammation trajectories precede cognitive impairment after experimental meningitis—evidence from an in vivo PET study

by Vijayasree V. Giridharan, Allan Collodel, Jaqueline S. Generoso, Giselli Scaini, Rico Wassather, Sudhakar Selvaraj, Rodrigo Hasbun, Felipe Dal-Pizzol, Fabricia Petronilho, Tatiana Barichello
Published 2020-01-01

3,4-Dihydroxybenzalacetone (DBL) Prevents Aging-Induced Myocardial Changes in Senescence-Accelerated Mouse-Prone 8 (SAMP8) Mice

by Vijayasree V. Giridharan, Vengadeshprabhu Karupppagounder, Somasundaram Arumugam, Yutaka Nakamura, Ashrith Guha, Tatiana Barichello, Joao Quevedo, Kenichi Watanabe, Tetsuya Konishi, Rajarajan A. Thandavarayan
Published 2020-03-01

Modulation of Macrophage Polarization and HMGB1-TLR2/TLR4 Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice.

by Vengadeshprabhu Karuppagounder, Vijayasree V Giridharan, Somasundaram Arumugam, Remya Sreedhar, Suresh S Palaniyandi, Prasanna Krishnamurthy, Joao Quevedo, Kenichi Watanabe, Tetsuya Konishi, Rajarajan A Thandavarayan
Published 2016-01-01

Schisandrin B Ameliorates ICV-Infused Amyloid β Induced Oxidative Stress and Neuronal Dysfunction through Inhibiting RAGE/NF-κB/MAPK and Up-Regulating HSP/Beclin Expression.

by Vijayasree V Giridharan, Rajarajan A Thandavarayan, Somasundaram Arumugam, Makoto Mizuno, Hiroyuki Nawa, Kenji Suzuki, Kam M Ko, Prasanna Krishnamurthy, Kenichi Watanabe, Tetsuya Konishi
Published 2015-01-01

Clozapine Prevents Poly (I:C) Induced Inflammation by Modulating NLRP3 Pathway in Microglial Cells

by Vijayasree V. Giridharan, Giselli Scaini, Gabriela D. Colpo, Tejaswini Doifode, Omar F. Pinjari, Antônio L. Teixeira, Fabricia Petronilho, Danielle Macêdo, João Quevedo, Tatiana Barichello
Published 2020-02-01

Small molecule disruption of G protein βγ subunit signaling reprograms human macrophage phenotype and prevents autoimmune myocarditis in rats.

by Vengadeshprabhu Karuppagounder, Anamika Bajpai, Shu Meng, Somasundaram Arumugam, Remya Sreedhar, Vijayasree V Giridharan, Ashrith Guha, Arvind Bhimaraj, Keith A Youker, Suresh S Palaniyandi, Harry Karmouty-Quintana, Fadia Kamal, Kara L Spiller, Kenichi Watanabe, Rajarajan A Thandavarayan
Published 2018-01-01