NLRP3 Inflammasome: A Possible Link Between Obesity-Associated Low-Grade Chronic Inflammation and Colorectal Cancer Development

by Patricia Ahechu, Gabriel Zozaya, Pablo Martí, José Luis Hernández-Lizoáin, Jorge Baixauli, Xabier Unamuno, Xabier Unamuno, Gema Frühbeck, Gema Frühbeck, Gema Frühbeck, Gema Frühbeck, Victoria Catalán, Victoria Catalán, Victoria Catalán
Published 2018-12-01

Leptin Inhibits the Proliferation of Vascular Smooth Muscle Cells Induced by Angiotensin II through Nitric Oxide-Dependent Mechanisms

by Amaia Rodríguez, Javier Gómez-Ambrosi, Victoria Catalán, Ana Fortuño, Gema Frühbeck
Published 2010-01-01

Normalization of adiponectin concentrations by leptin replacement in ob/ob mice is accompanied by reductions in systemic oxidative stress and inflammation

by Gema Frühbeck, Victoria Catalán, Amaia Rodríguez, Beatriz Ramírez, Sara Becerril, Piero Portincasa, Javier Gómez-Ambrosi
Published 2017-06-01

Leptin administration favors muscle mass accretion by decreasing FoxO3a and increasing PGC-1alpha in ob/ob mice.

by Neira Sáinz, Amaia Rodríguez, Victoria Catalán, Sara Becerril, Beatriz Ramírez, Javier Gómez-Ambrosi, Gema Frühbeck
Published 2009-09-01

Leptin Administration Downregulates the Increased Expression Levels of Genes Related to Oxidative Stress and Inflammation in the Skeletal Muscle of ob/ob Mice

by Neira Sáinz, Amaia Rodríguez, Victoria Catalán, Sara Becerril, Beatriz Ramírez, Javier Gómez-Ambrosi, Gema Frühbeck
Published 2010-01-01

<i>iNOS</i> Gene Ablation Prevents Liver Fibrosis in Leptin-Deficient <i>ob/ob </i>Mice

by Sara Becerril, Amaia Rodríguez, Victoria Catalán, Beatriz Ramírez, Xabier Unamuno, Javier Gómez-Ambrosi, Gema Frühbeck
Published 2019-02-01

Functional Relationship between Leptin and Nitric Oxide in Metabolism

by Sara Becerril, Amaia Rodríguez, Victoria Catalán, Beatriz Ramírez, Xabier Unamuno, Piero Portincasa, Javier Gómez-Ambrosi, Gema Frühbeck
Published 2019-09-01

Adiponectin-leptin Ratio is a Functional Biomarker of Adipose Tissue Inflammation

by Gema Frühbeck, Victoria Catalán, Amaia Rodríguez, Beatriz Ramírez, Sara Becerril, Javier Salvador, Inmaculada Colina, Javier Gómez-Ambrosi
Published 2019-02-01

Involvement of the leptin-adiponectin axis in inflammation and oxidative stress in the metabolic syndrome

by Gema Frühbeck, Victoria Catalán, Amaia Rodríguez, Beatriz Ramírez, Sara Becerril, Javier Salvador, Piero Portincasa, Inmaculada Colina, Javier Gómez-Ambrosi
Published 2017-07-01

Deletion of inducible nitric-oxide synthase in leptin-deficient mice improves brown adipose tissue function.

by Sara Becerril, Amaia Rodríguez, Victoria Catalán, Neira Sáinz, Beatriz Ramírez, María Collantes, Iván Peñuelas, Javier Gómez-Ambrosi, Gema Frühbeck
Published 2010-06-01

Leptin reduces the expression and increases the phosphorylation of the negative regulators of GLUT4 traffic TBC1D1 and TBC1D4 in muscle of ob/ob mice.

by Neira Sáinz, Amaia Rodríguez, Victoria Catalán, Sara Becerril, Beatriz Ramírez, Andoni Lancha, Emma Burgos-Ramos, Javier Gómez-Ambrosi, Gema Frühbeck
Published 2012-01-01

Caloric Restriction Prevents Metabolic Dysfunction and the Changes in Hypothalamic Neuropeptides Associated with Obesity Independently of Dietary Fat Content in Rats

by Marina Martín, Amaia Rodríguez, Javier Gómez-Ambrosi, Beatriz Ramírez, Sara Becerril, Victoria Catalán, Miguel López, Carlos Diéguez, Gema Frühbeck, María A. Burrell
Published 2021-06-01

Osteopontin deletion prevents the development of obesity and hepatic steatosis via impaired adipose tissue matrix remodeling and reduced inflammation and fibrosis in adipose tissue...

by Andoni Lancha, Amaia Rodríguez, Victoria Catalán, Sara Becerril, Neira Sáinz, Beatriz Ramírez, María A Burrell, Javier Salvador, Gema Frühbeck, Javier Gómez-Ambrosi
Published 2014-01-01

Dermatopontin, A Novel Adipokine Promoting Adipose Tissue Extracellular Matrix Remodelling and Inflammation in Obesity

by Xabier Unamuno, Javier Gómez-Ambrosi, Beatriz Ramírez, Amaia Rodríguez, Sara Becerril, Víctor Valentí, Rafael Moncada, Camilo Silva, Javier Salvador, Gema Frühbeck, Victoria Catalán
Published 2020-04-01

Epigenome-wide DNA methylation profiling of periprostatic adipose tissue in prostate cancer patients with excess adiposity—a pilot study

by Yan Cheng, Cátia Monteiro, Andreia Matos, Jiaying You, Avelino Fraga, Carina Pereira, Victoria Catalán, Amaia Rodríguez, Javier Gómez-Ambrosi, Gema Frühbeck, Ricardo Ribeiro, Pingzhao Hu
Published 2018-04-01

Circulating Concentrations of GDF11 are Positively Associated with TSH Levels in Humans

by Juan Añón-Hidalgo, Victoria Catalán, Amaia Rodríguez, Beatriz Ramírez, Adrián Idoate-Bayón, Camilo Silva, Carmen Mugueta, Juan C. Galofré, Javier Salvador, Gema Frühbeck, Javier Gómez-Ambrosi
Published 2019-06-01

Resting Energy Expenditure Is Not Altered in Children and Adolescents with Obesity. Effect of Age and Gender and Association with Serum Leptin Levels

by J. Karina Zapata, Victoria Catalán, Amaia Rodríguez, Beatriz Ramírez, Camilo Silva, Javier Escalada, Javier Salvador, Giuseppe Calamita, M. Cristina Azcona-Sanjulian, Gema Frühbeck, Javier Gómez-Ambrosi
Published 2021-04-01

Aquaporin-11 Contributes to TGF-β1-Induced Endoplasmic Reticulum Stress in Human Visceral Adipocytes: Role in Obesity-Associated Inflammation

by Gema Frühbeck, Inmaculada Balaguer, Leire Méndez-Giménez, Víctor Valentí, Sara Becerril, Victoria Catalán, Javier Gómez-Ambrosi, Camilo Silva, Javier Salvador, Giuseppe Calamita, María M. Malagón, Amaia Rodríguez
Published 2020-06-01

Increase of the Adiponectin/Leptin Ratio in Patients with Obesity and Type 2 Diabetes after Roux-en-Y Gastric Bypass

by Xabier Unamuno, Maitane Izaguirre, Javier Gómez-Ambrosi, Amaia Rodríguez, Beatriz Ramírez, Sara Becerril, Víctor Valentí, Rafael Moncada, Camilo Silva, Javier Salvador, Piero Portincasa, Gema Frühbeck, Victoria Catalán
Published 2019-09-01

Increased Obesity-Associated Circulating Levels of the Extracellular Matrix Proteins Osteopontin, Chitinase-3 Like-1 and Tenascin C Are Associated with Colon Cancer.

by Victoria Catalán, Javier Gómez-Ambrosi, Amaia Rodríguez, Beatriz Ramírez, Maitane Izaguirre, José Luis Hernández-Lizoain, Jorge Baixauli, Pablo Martí, Víctor Valentí, Rafael Moncada, Camilo Silva, Javier Salvador, Gema Frühbeck
Published 2016-01-01