Genetically Corrected iPSC-Derived Neural Stem Cell Grafts Deliver Enzyme Replacement to Affect CNS Disease in Sanfilippo B Mice

by Don Clarke, Yewande Pearse, Shih-hsin Kan, Steven Q. Le, Valentina Sanghez, Jonathan D. Cooper, Patricia I. Dickson, Michelina Iacovino
Published 2018-09-01

Notch activation is required for downregulation of HoxA3-dependent endothelial cell phenotype during blood formation.

by Valentina Sanghez, Anna Luzzi, Don Clarke, Dustin Kee, Steven Beuder, Danielle Rux, Mitsujiro Osawa, Joaquín Madrenas, Tsui-Fen Chou, Michael Kyba, Michelina Iacovino
Published 2017-01-01

Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation

by Yu-Lin Kuang, Antonio Munoz, Gilbert Nalula, Katherine E. Santostefano, Valentina Sanghez, Gabriela Sanchez, Naohiro Terada, Aras N. Mattis, Michelina Iacovino, Carlos Iribarren, Ronald M. Krauss, Marisa W. Medina
Published 2019-05-01

A Humoral Immune Response Alters the Distribution of Enzyme Replacement Therapy in Murine Mucopolysaccharidosis Type I

by Steven Q. Le, Shih-hsin Kan, Don Clarke, Valentina Sanghez, Martin Egeland, Kristen N. Vondrak, Terence M. Doherty, Moin U. Vera, Michelina Iacovino, Jonathan D. Cooper, Mark S. Sands, Patricia I. Dickson
Published 2018-03-01