First eight residues of apolipoprotein A-I mediate the C-terminus control of helical bundle unfolding and its lipidation.

by Gregory Brubaker, Shuhui W Lorkowski, Kailash Gulshan, Stanley L Hazen, Valentin Gogonea, Jonathan D Smith
Published 2020-01-01

The zinc-binding domain of mammalian prolyl-tRNA synthetase is indispensable for catalytic activity and organism viability

by Kommireddy Vasu, Iyappan Ramachandiran, Fulvia Terenzi, Debjit Khan, Arnab China, Krishnendu Khan, Aayushi Chechi, Camelia Baleanu-Gogonea, Valentin Gogonea, Paul L. Fox
Published 2021-03-01

Protein Backbone and Average Particle Dynamics in Reconstituted Discoidal and Spherical HDL Probed by Hydrogen Deuterium Exchange and Elastic Incoherent Neutron Scattering

by Valentin Gogonea, Judith Peters, Gary S. Gerstenecker, Celalettin Topbas, Liming Hou, Jérôme Combet, Joseph A. DiDonato, Jonathan D. Smith, Kerry-Anne Rye, Stanley L. Hazen
Published 2020-01-01

Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice

by George D. Dalton, Seh-Hoon Oh, Linda Tang, Stephanie Zhang, Amanda L. Brown, Venkateshwari Varadharajan, Camelia Baleanu-Gogonea, Valentin Gogonea, Preeti Pathak, J. Mark Brown, Anna Mae Diehl
Published 2021-09-01

Quantification of bile acids: a mass spectrometry platform for studying gut microbe connection to metabolic diseases[S]

by Ibrahim Choucair, Ina Nemet, Lin Li, Margaret A. Cole, Sarah M. Skye, Jennifer D. Kirsop, Michael A. Fischbach, Valentin Gogonea, J. Mark Brown, W. H. Wilson Tang, Stanley L. Hazen
Published 2020-02-01

The low-resolution structure of nHDL reconstituted with DMPC with and without cholesterol reveals a mechanism for particle expansion[S]

by Valentin Gogonea, Gary S. Gerstenecker, Zhiping Wu, Xavier Lee, Celalettin Topbas, Matthew A. Wagner, Thomas C. Tallant, Jonathan D. Smith, Philip Callow, Vitaliy Pipich, Hélène Malet, Guy Schoehn, Joseph A. DiDonato, Stanley L. Hazen
Published 2013-04-01

Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease

by Robert N Helsley, Venkateshwari Varadharajan, Amanda L Brown, Anthony D Gromovsky, Rebecca C Schugar, Iyappan Ramachandiran, Kevin Fung, Mohammad Nasser Kabbany, Rakhee Banerjee, Chase K Neumann, Chelsea Finney, Preeti Pathak, Danny Orabi, Lucas J Osborn, William Massey, Renliang Zhang, Anagha Kadam, Brian E Sansbury, Calvin Pan, Jessica Sacks, Richard G Lee, Rosanne M Crooke, Mark J Graham, Madeleine E Lemieux, Valentin Gogonea, John P Kirwan, Daniela S Allende, Mete Civelek, Paul L Fox, Lawrence L Rudel, Aldons J Lusis, Matthew Spite, J Mark Brown
Published 2019-10-01