Prolyl 4‐hydroxylase subunit alpha 1 (P4HA1) is a biomarker of poor prognosis in primary melanomas, and its depletion inhibits melanoma cell invasion and disrupts tumor blood vesse...

by Johanna Eriksson, Vadim Le Joncour, Tiina Jahkola, Susanna Juteau, Pirjo Laakkonen, Olli Saksela, Erkki Hölttä
Published 2020-04-01

CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity

by Pauliina Filppu, Jayendrakishore Tanjore Ramanathan, Kirsi J. Granberg, Erika Gucciardo, Hannu Haapasalo, Kaisa Lehti, Matti Nykter, Vadim Le Joncour, Pirjo Laakkonen
Published 2021-05-01

Circumventing Drug Treatment? Intrinsic Lethal Effects of Polyethyleneimine (PEI)-Functionalized Nanoparticles on Glioblastoma Cells Cultured in Stem Cell Conditions

by Neeraj Prabhakar, Joni Merisaari, Vadim Le Joncour, Markus Peurla, Didem Şen Karaman, Eudald Casals, Pirjo Laakkonen, Jukka Westermarck, Jessica M. Rosenholm
Published 2021-05-01

Evaluation of the impact of the cancer therapy everolimus on the central nervous system in mice.

by Martine Dubois, Vadim Le Joncour, Marie-Christine Tonon, Youssef Anouar, François Proust, Fabrice Morin, Pierrick Gandolfo, Florence Joly, Pascal Hilber, Hélène Castel
Published 2014-01-01

Vulnerability of invasive glioblastoma cells to lysosomal membrane destabilization

by Vadim Le Joncour, Pauliina Filppu, Maija Hyvönen, Minna Holopainen, S Pauliina Turunen, Harri Sihto, Isabel Burghardt, Heikki Joensuu, Olli Tynninen, Juha Jääskeläinen, Michael Weller, Kaisa Lehti, Reijo Käkelä, Pirjo Laakkonen
Published 2019-06-01

Octreotide Conjugates for Tumor Targeting and Imaging

by Eduard Figueras, Ana Martins, Adina Borbély, Vadim Le Joncour, Paola Cordella, Raffaella Perego, Daniela Modena, Paolo Pagani, Simone Esposito, Giulio Auciello, Marcel Frese, Paola Gallinari, Pirjo Laakkonen, Christian Steinkühler, Norbert Sewald
Published 2019-05-01

Targeting the Urotensin II/UT G Protein-Coupled Receptor to Counteract Angiogenesis and Mesenchymal Hypoxia/Necrosis in Glioblastoma

by Vadim Le Joncour, Pierre-Olivier Guichet, Kleouforo-Paul Dembélé, Alexandre Mutel, Daniele Campisi, Nicolas Perzo, Laurence Desrues, Romain Modzelewski, Pierre-Olivier Couraud, Jérôme Honnorat, Jérôme Honnorat, Jérôme Honnorat, François-Xavier Ferracci, François-Xavier Ferracci, Florent Marguet, Annie Laquerrière, Pierre Vera, Pierre Bohn, Olivier Langlois, Olivier Langlois, Fabrice Morin, Pierrick Gandolfo, Hélène Castel
Published 2021-04-01