Rapid Generation of In Vitro Multicellular Spheroids for the Study of Monoclonal Antibody Therapy

by Yen T. Phung, Dario Barbone, V. Courtney Broaddus, Mitchell Ho
Published 2011-01-01

The development and characterization of a human mesothelioma in vitro 3D model to investigate immunotoxin therapy.

by Xinran Xiang, Yen Phung, Mingqian Feng, Kunio Nagashima, Jingli Zhang, V Courtney Broaddus, Raffit Hassan, David Fitzgerald, Mitchell Ho
Published 2011-01-01

Autophagy Correlates with the Therapeutic Responsiveness of Malignant Pleural Mesothelioma in 3D Models.

by Dario Barbone, Carlo Follo, Nohemy Echeverry, Victor H Gerbaudo, Astero Klabatsa, Raphael Bueno, Emanuela Felley-Bosco, V Courtney Broaddus
Published 2015-01-01

Analysis of Gene Expression in 3D Spheroids Highlights a Survival Role for ASS1 in Mesothelioma.

by Dario Barbone, Loes Van Dam, Carlo Follo, Puthen V Jithesh, Shu-Dong Zhang, William G Richards, Raphael Bueno, Dean A Fennell, V Courtney Broaddus
Published 2016-01-01

Vorinostat eliminates multicellular resistance of mesothelioma 3D spheroids via restoration of Noxa expression.

by Dario Barbone, Priscilla Cheung, Sailaja Battula, Sara Busacca, Steven G Gray, Daniel B Longley, Raphael Bueno, David J Sugarbaker, Dean A Fennell, V Courtney Broaddus
Published 2012-01-01

Correction: BAK and NOXA Are Critical Determinants of Mitochondrial Apoptosis Induced by Bortezomib in Mesothelioma

by Sara Busacca, Alex D. Chacko, Astero Klabatsa, Kenneth Arthur, Michael Sheaff, Dario Barbone, Luciano Mutti, Vignesh K. Gunasekharan, Julia J. Gorski, Mohamed El-Tanani, V. Courtney Broaddus, Giovanni Gaudino, Dean A. Fennell
Published 2013-01-01

BAK and NOXA are critical determinants of mitochondrial apoptosis induced by bortezomib in mesothelioma.

by Sara Busacca, Alex D Chacko, Astero Klabatsa, Kenneth Arthur, Michael Sheaff, Dario Barbone, Luciano Mutti, Vignesh K Gunasekharan, Julia J Gorski, Mohamed El-Tanani, V Courtney Broaddus, Giovanni Gaudino, Dean A Fennell
Published 2013-01-01

Correction: BAK and NOXA Are Critical Determinants of Mitochondrial Apoptosis Induced by Bortezomib in Mesothelioma.

by Sara Busacca, Alex D. Chacko, Astero Klabatsa, Kenneth Arthur, Michael Sheaff, Dario Barbone, Luciano Mutti, Vignesh K. Gunasekharan, Julia J. Gorski, Mohamed El-Tanani, V. Courtney Broaddus, Giovanni Gaudino, Dean A. Fennell
Published 2013-01-01