Functional characterization of FLT3 receptor signaling deregulation in acute myeloid leukemia by single cell network profiling (SCNP).

by David B Rosen, Mark D Minden, Steven M Kornblau, Aileen Cohen, Urte Gayko, Santosh Putta, John Woronicz, Erik Evensen, Wendy J Fantl, Alessandra Cesano
Published 2010-01-01

Functional pathway analysis using SCNP of FLT3 receptor pathway deregulation in AML provides prognostic information independent from mutational status.

by Alessandra Cesano, Santosh Putta, David B Rosen, Aileen C Cohen, Urte Gayko, Kavita Mathi, John Woronicz, Rachael E Hawtin, Larry Cripe, Zhuoxin Sun, Martin S Tallman, Elisabeth Paietta
Published 2013-01-01

Cell signaling-based classifier predicts response to induction therapy in elderly patients with acute myeloid leukemia.

by Alessandra Cesano, Cheryl L Willman, Kenneth J Kopecky, Urte Gayko, Santosh Putta, Brent Louie, Matt Westfall, Norman Purvis, David C Spellmeyer, Carol Marimpietri, Aileen C Cohen, James Hackett, Jing Shi, Michael G Walker, Zhuoxin Sun, Elisabeth Paietta, Martin S Tallman, Larry D Cripe, Susan Atwater, Frederick R Appelbaum, Jerald P Radich
Published 2015-01-01