Application of an Inclined Settler for Cell Culture-Based Influenza A Virus Production in Perfusion Mode

by Juliana Coronel, Gwendal Gränicher, Volker Sandig, Thomas Noll, Yvonne Genzel, Udo Reichl, Udo Reichl
Published 2020-07-01

Production of Defective Interfering Particles of Influenza A Virus in Parallel Continuous Cultures at Two Residence Times—Insights From qPCR Measurements and Viral Dynamics Modelin...

by Felipe Tapia, Tanja Laske, Milena A. Wasik, Markus Rammhold, Yvonne Genzel, Udo Reichl, Udo Reichl
Published 2019-10-01

Glycolysis is governed by growth regime and simple enzyme regulation in adherent MDCK cells.

by Markus Rehberg, Joachim B Ritter, Udo Reichl
Published 2014-10-01

Efficient and stable production of Modified Vaccinia Ankara virus in two-stage semi-continuous and in continuous stirred tank cultivation systems.

by Felipe Tapia, Ingo Jordan, Yvonne Genzel, Udo Reichl
Published 2017-01-01

Elements in the Development of a Production Process for Modified Vaccinia Virus Ankara

by Volker Sandig, Udo Reichl, Verena Lohr, Yvonne Genzel, Ingo Jordan
Published 2013-11-01

Cell-Free Glycoengineering of the Recombinant SARS-CoV-2 Spike Glycoprotein

by Johannes Ruhnau, Valerian Grote, Mariana Juarez-Osorio, Dunja Bruder, Dunja Bruder, Reza Mahour, Erdmann Rapp, Erdmann Rapp, Thomas F. T. Rexer, Udo Reichl, Udo Reichl
Published 2021-08-01

Impact of host cell line adaptation on quasispecies composition and glycosylation of influenza A virus hemagglutinin.

by Jana Verena Roedig, Erdmann Rapp, Dirk Höper, Yvonne Genzel, Udo Reichl
Published 2011-01-01

Multiscale modeling of influenza A virus replication in cell cultures predicts infection dynamics for highly different infection conditions.

by Daniel Rüdiger, Sascha Young Kupke, Tanja Laske, Pawel Zmora, Udo Reichl
Published 2019-02-01

Continuous influenza virus production in a tubular bioreactor system provides stable titers and avoids the "von Magnus effect".

by Felipe Tapia, Daniel Wohlfarth, Volker Sandig, Ingo Jordan, Yvonne Genzel, Udo Reichl
Published 2019-01-01

Site-specific N-glycosylation analysis of animal cell culture-derived Zika virus proteins

by Alexander Pralow, Alexander Nikolay, Arnaud Leon, Yvonne Genzel, Erdmann Rapp, Udo Reichl
Published 2021-03-01

Identification of growth phases and influencing factors in cultivations with AGE1.HN cells using set-based methods.

by Steffen Borchers, Susann Freund, Alexander Rath, Stefan Streif, Udo Reichl, Rolf Findeisen
Published 2013-01-01

Multiscale modeling of influenza A virus infection supports the development of direct-acting antivirals.

by Frank S Heldt, Timo Frensing, Antje Pflugmacher, Robin Gröpler, Britta Peschel, Udo Reichl
Published 2013-01-01

A Robust and Universal Metaproteomics Workflow for Research Studies and Routine Diagnostics Within 24 h Using Phenol Extraction, FASP Digest, and the MetaProteomeAnalyzer

by Robert Heyer, Kay Schallert, Anja Büdel, Roman Zoun, Sebastian Dorl, Alexander Behne, Fabian Kohrs, Sebastian Püttker, Corina Siewert, Thilo Muth, Gunter Saake, Udo Reichl, Udo Reichl, Dirk Benndorf, Dirk Benndorf
Published 2019-08-01

A system for production of defective interfering particles in the absence of infectious influenza A virus.

by Najat Bdeir, Prerna Arora, Sabine Gärtner, Markus Hoffmann, Udo Reichl, Stefan Pöhlmann, Michael Winkler
Published 2019-01-01

RedCom: A strategy for reduced metabolic modeling of complex microbial communities and its application for analyzing experimental datasets from anaerobic digestion.

by Sabine Koch, Fabian Kohrs, Patrick Lahmann, Thomas Bissinger, Stefan Wendschuh, Dirk Benndorf, Udo Reichl, Steffen Klamt
Published 2019-02-01

Enzymatic Cascades for Tailored ¹³C₆ and ¹⁵N Enriched Human Milk Oligosaccharides

by Thomas Fischöder, Samanta Cajic, Valerian Grote, Raphael Heinzler, Udo Reichl, Matthias Franzreb, Erdmann Rapp, Lothar Elling
Published 2019-09-01

Continuous influenza virus production in cell culture shows a periodic accumulation of defective interfering particles.

by Timo Frensing, Frank Stefan Heldt, Antje Pflugmacher, Ilona Behrendt, Ingo Jordan, Dietrich Flockerzi, Yvonne Genzel, Udo Reichl
Published 2013-01-01

Single-Cell Analysis Uncovers a Vast Diversity in Intracellular Viral Defective Interfering RNA Content Affecting the Large Cell-to-Cell Heterogeneity in Influenza A Virus Replicat...

by Sascha Young Kupke, Lam-Ha Ly, Stefan Thomas Börno, Alexander Ruff, Bernd Timmermann, Martin Vingron, Stefan Haas, Udo Reichl
Published 2020-01-01

Model-based analysis of influenza A virus replication in genetically engineered cell lines elucidates the impact of host cell factors on key kinetic parameters of virus growth.

by Tanja Laske, Mandy Bachmann, Melanie Dostert, Alexander Karlas, Dagmar Wirth, Timo Frensing, Thomas F Meyer, Hansjörg Hauser, Udo Reichl
Published 2019-04-01

Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles

by Marc D. Hein, Prerna Arora, Pavel Marichal-Gallardo, Michael Winkler, Yvonne Genzel, Stefan Pöhlmann, Klaus Schughart, Sascha Y. Kupke, Udo Reichl
Published 2021-05-01