DNA sequence variants in PPARGC1A, a gene encoding a coactivator of the ω-3 LCPUFA sensing PPAR-RXR transcription complex, are associated with NV AMD and AMD-associated loci in gen...

by John Paul SanGiovanni, Jing Chen, Przemyslaw Sapieha, Christopher M Aderman, Andreas Stahl, Traci E Clemons, Emily Y Chew, Lois E H Smith
Published 2013-01-01

Genetic disruption of serine biosynthesis is a key driver of macular telangiectasia type 2 aetiology and progression

by Roberto Bonelli, Brendan R. E. Ansell, Luca Lotta, Thomas Scerri, Traci E. Clemons, Irene Leung, The MacTel Consortium, Tunde Peto, Alan C. Bird, Ferenc B. Sallo, Claudia Langenberg, Melanie Bahlo
Published 2021-03-01

Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are associated with increased risk of age-related macular degeneration.

by John Paul SanGiovanni, Dan E Arking, Sudha K Iyengar, Michael Elashoff, Traci E Clemons, George F Reed, Alice K Henning, Theru A Sivakumaran, Xuming Xu, Andrew DeWan, Elvira Agrón, Elena Rochtchina, Carolyn M Sue, Jie Jin Wang, Paul Mitchell, Josephine Hoh, Peter J Francis, Michael L Klein, Emily Y Chew, Aravinda Chakravarti
Published 2009-01-01