Functions of Osteocalcin in Bone, Pancreas, Testis, and Muscle

by Toshihisa Komori
Published 2020-10-01

Molecular Processes in Chondrocyte Biology

by Toshihisa Komori
Published 2020-06-01

Cell Death in Chondrocytes, Osteoblasts, and Osteocytes

by Toshihisa Komori
Published 2016-12-01

Regulation of Proliferation, Differentiation and Functions of Osteoblasts by Runx2

by Toshihisa Komori
Published 2019-04-01

Lack of reproducibility in osteocalcin-deficient mice.

by Takeshi Moriishi, Toshihisa Komori
Published 2020-06-01

Thrombospondin-1 Is a Putative Target Gene of Runx2 and Runx3

by Wenguang Liu, Toshihisa Komori, Xianlu Zeng, Xueqing Ba, Linghui Wang, Xiuming Shi, Vishwa Deepak
Published 2013-07-01

Bcl2 deficiency activates FoxO through Akt inactivation and accelerates osteoblast differentiation.

by Takeshi Moriishi, Yosuke Kawai, Hisato Komori, Satoshi Rokutanda, Yutaka Eguchi, Yoshihide Tsujimoto, Izumi Asahina, Toshihisa Komori
Published 2014-01-01

Osteocyte network; a negative regulatory system for bone mass augmented by the induction of Rankl in osteoblasts and Sost in osteocytes at unloading.

by Takeshi Moriishi, Ryo Fukuyama, Masako Ito, Toshihiro Miyazaki, Takafumi Maeno, Yosuke Kawai, Hisato Komori, Toshihisa Komori
Published 2012-01-01

Expression of a Constitutively Active Form of <i>Hck</i> in Chondrocytes Activates Wnt and Hedgehog Signaling Pathways, and Induces Chondrocyte Proliferation in Mice

by Viviane K. S. Kawata Matsuura, Carolina Andrea Yoshida, Hisato Komori, Chiharu Sakane, Kei Yamana, Qing Jiang, Toshihisa Komori
Published 2020-04-01

Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts.

by Xin Qin, Qing Jiang, Kenichi Nagano, Takeshi Moriishi, Toshihiro Miyazaki, Hisato Komori, Kosei Ito, Klaus von der Mark, Chiharu Sakane, Hitomi Kaneko, Toshihisa Komori
Published 2020-11-01

Antxr1, Which is a Target of Runx2, Regulates Chondrocyte Proliferation and Apoptosis

by Qing Jiang, Xin Qin, Carolina Andrea Yoshida, Hisato Komori, Kei Yamana, Shinsuke Ohba, Hironori Hojo, Brad St. Croix, Viviane K. S. Kawata-Matsuura, Toshihisa Komori
Published 2020-03-01

Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle mass.

by Takeshi Moriishi, Ryosuke Ozasa, Takuya Ishimoto, Takayoshi Nakano, Tomoka Hasegawa, Toshihiro Miyazaki, Wenguang Liu, Ryo Fukuyama, Yuying Wang, Hisato Komori, Xin Qin, Norio Amizuka, Toshihisa Komori
Published 2020-05-01

Dmrt2 promotes transition of endochondral bone formation by linking Sox9 and Runx2

by Koichiro Ono, Kenji Hata, Eriko Nakamura, Shota Ishihara, Sachi Kobayashi, Masako Nakanishi, Michiko Yoshida, Yoshifumi Takahata, Tomohiko Murakami, Seiichi Takenoshita, Toshihisa Komori, Riko Nishimura, Toshiyuki Yoneda
Published 2021-03-01

MAML1 enhances the transcriptional activity of Runx2 and plays a role in bone development.

by Takashi Watanabe, Toshinao Oyama, Maki Asada, Daisuke Harada, Yoshiaki Ito, Masayo Inagawa, Yutaka Suzuki, Sumio Sugano, Ken-ichi Katsube, Gerard Karsenty, Toshihisa Komori, Motoo Kitagawa, Hiroshi Asahara
Published 2013-01-01

Antagonistic Functions of USAG-1 and RUNX2 during Tooth Development.

by Yumiko Togo, Katsu Takahashi, Kazuyuki Saito, Honoka Kiso, Hiroko Tsukamoto, Boyen Huang, Motoko Yanagita, Manabu Sugai, Hidemitsu Harada, Toshihisa Komori, Akira Shimizu, Mary MacDougall, Kazuhisa Bessho
Published 2016-01-01

Overexpression of Bcl2 in osteoblasts inhibits osteoblast differentiation and induces osteocyte apoptosis.

by Takeshi Moriishi, Zenjiro Maruyama, Ryo Fukuyama, Masako Ito, Toshihiro Miyazaki, Hideki Kitaura, Hidetake Ohnishi, Tatsuya Furuichi, Yosuke Kawai, Ritsuko Masuyama, Hisato Komori, Kenji Takada, Hiroshi Kawaguchi, Toshihisa Komori
Published 2011-01-01

Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy

by Mengyu Yang, Atsushi Arai, Nobuyuki Udagawa, Toru Hiraga, Zhao Lijuan, Susumu Ito, Toshihisa Komori, Takeshi Moriishi, Koichi Matsuo, Kouji Shimoda, Ali H. Zahalka, Yasuhiro Kobayashi, Naoyuki Takahashi, Toshihide Mizoguchi
Published 2017-07-01

Local application of Usag-1 siRNA can promote tooth regeneration in Runx2-deficient mice

by Sayaka Mishima, Katsu Takahashi, Honoka Kiso, Akiko Murashima-Suginami, Yoshihito Tokita, Jun-Ichiro Jo, Ryuji Uozumi, Yukiko Nambu, Boyen Huang, Hidemitsu Harada, Toshihisa Komori, Manabu Sugai, Yasuhiko Tabata, Kazuhisa Bessho
Published 2021-07-01

SP7 inhibits osteoblast differentiation at a late stage in mice.

by Carolina A Yoshida, Hisato Komori, Zenjiro Maruyama, Toshihiro Miyazaki, Keishi Kawasaki, Tatsuya Furuichi, Ryo Fukuyama, Masako Mori, Kei Yamana, Kouhei Nakamura, Wenguang Liu, Satoru Toyosawa, Takeshi Moriishi, Hiroshi Kawaguchi, Kenji Takada, Toshihisa Komori
Published 2012-01-01