Spastin depletion increases tubulin polyglutamylation and impairs kinesin-mediated neuronal transport, leading to working and associative memory deficits.

by André T Lopes, Torben J Hausrat, Frank F Heisler, Kira V Gromova, Franco L Lombino, Timo Fischer, Laura Ruschkies, Petra Breiden, Edda Thies, Irm Hermans-Borgmeyer, Michaela Schweizer, Jürgen R Schwarz, Christian Lohr, Matthias Kneussel
Published 2020-08-01

SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals

by Maria Andres-Alonso, Mohamed Raafet Ammar, Ioana Butnaru, Guilherme M. Gomes, Gustavo Acuña Sanhueza, Rajeev Raman, PingAn Yuanxiang, Maximilian Borgmeyer, Jeffrey Lopez-Rojas, Syed Ahsan Raza, Nicola Brice, Torben J. Hausrat, Tamar Macharadze, Silvia Diaz-Gonzalez, Mark Carlton, Antonio Virgilio Failla, Oliver Stork, Michaela Schweizer, Eckart D. Gundelfinger, Matthias Kneussel, Christina Spilker, Anna Karpova, Michael R. Kreutz
Published 2019-11-01