TREM2/PLCγ2 signalling in immune cells: function, structural insight, and potential therapeutic modulation

by Lorenza Magno, Tom D. Bunney, Emma Mead, Fredrik Svensson, Magda N. Bictash
Published 2021-04-01

Targeting the Src Pathway Enhances the Efficacy of Selective FGFR Inhibitors in Urothelial Cancers with FGFR3 Alterations

by Nadia Carvalho Lima, Eliza Atkinson, Tom D. Bunney, Matilda Katan, Paul H. Huang
Published 2020-05-01

The Effect of Mutations on Drug Sensitivity and Kinase Activity of Fibroblast Growth Factor Receptors: A Combined Experimental and Theoretical Study

by Tom D. Bunney, Shunzhou Wan, Nethaji Thiyagarajan, Ludovico Sutto, Sarah V. Williams, Paul Ashford, Hans Koss, Margaret A. Knowles, Francesco L. Gervasio, Peter V. Coveney, Matilda Katan
Published 2015-03-01

Structural insights and activating mutations in diverse pathologies define mechanisms of deregulation for phospholipase C gamma enzymes

by Yang Liu, Tom D. Bunney, Sakshi Khosa, Kévin Macé, Katharina Beckenbauer, Trevor Askwith, Sarah Maslen, Christopher Stubbs, Taiana M. de Oliveira, Kasim Sader, Mark Skehel, Anne-Claude Gavin, Christopher Phillips, Matilda Katan
Published 2020-01-01