TCR stimulation strength is inversely associated with establishment of functional brain-resident memory CD8 T cells during persistent viral infection.

by Saumya Maru, Ge Jin, Todd D Schell, Aron E Lukacher
Published 2017-04-01

Beta blocker use correlates with better overall survival in metastatic melanoma patients and improves the efficacy of immunotherapies in mice

by Kathleen M. Kokolus, Ying Zhang, Jeffrey M. Sivik, Carla Schmeck, Junjia Zhu, Elizabeth A. Repasky, Joseph J. Drabick, Todd. D. Schell
Published 2018-03-01

Mouse papillomavirus infection persists in mucosal tissues of an immunocompetent mouse strain and progresses to cancer

by Nancy M. Cladel, Lynn R. Budgeon, Karla K. Balogh, Timothy K. Cooper, Sarah A. Brendle, Neil D. Christensen, Todd D. Schell, Jiafen Hu
Published 2017-12-01

Suppression of immunodominant antitumor and antiviral CD8+ T cell responses by indoleamine 2,3-dioxygenase.

by Mateusz Rytelewski, Courtney E Meilleur, Maryam Atef Yekta, Peter A Szabo, Nitan Garg, Todd D Schell, Anthony M Jevnikar, Shayan Sharif, Bhagirath Singh, S M Mansour Haeryfar
Published 2014-01-01

Sunitinib represses regulatory T cells to overcome immunotolerance in a murine model of hepatocellular cancer

by Dai Liu, Guangfu Li, Diego M. Avella, Eric T. Kimchi, Jussuf T. Kaifi, Mark P. Rubinstein, E. Ramsay Camp, Don C. Rockey, Todd D. Schell, Kevin F. Staveley-O'Carroll
Published 2018-01-01

Blimp-1 impairs T cell function via upregulation of TIGIT and PD-1 in patients with acute myeloid leukemia

by Liuluan Zhu, Yaxian Kong, Jianhong Zhang, David F. Claxton, W. Christopher Ehmann, Witold B. Rybka, Neil D. Palmisiano, Ming Wang, Bei Jia, Michael Bayerl, Todd D. Schell, Raymond J. Hohl, Hui Zeng, Hong Zheng
Published 2017-06-01

Schweinfurthin natural products induce regression of murine melanoma and pair with anti-PD-1 therapy to facilitate durable tumor immunity

by Kathleen M. Kokolus, Jeremy S. Haley, Emily J. Koubek, Raghavendra Gowda, Saketh S. Dinavahi, Arati Sharma, David F. Claxton, Klaus F. Helm, Joseph J. Drabick, Gavin P. Robertson, Jeffrey D. Neighbors, Raymond J. Hohl, Todd D. Schell
Published 2019-02-01