Neurodegeneration Upon Dysfunction of Endosomal/Lysosomal CLC Chloride Transporters

by Shroddha Bose, Hailan He, Hailan He, Tobias Stauber, Tobias Stauber
Published 2021-02-01

The Volume-Regulated Anion Channel LRRC8/VRAC Is Dispensable for Cell Proliferation and Migration

by Tianbao Liu, Tobias Stauber
Published 2019-05-01

The G215R mutation in the Cl-/H+-antiporter ClC-7 found in ADO II osteopetrosis does not abolish function but causes a severe trafficking defect.

by Patrick Schulz, Johannes Werner, Tobias Stauber, Kim Henriksen, Klaus Fendler
Published 2010-09-01

A Mathematical Model of Lysosomal Ion Homeostasis Points to Differential Effects of Cl⁻ Transport in Ca²⁺ Dynamics

by Rosario Astaburuaga, Orlando Daniel Quintanar Haro, Tobias Stauber, Angela Relógio
Published 2019-10-01

A FRET sensor of C-terminal movement reveals VRAC activation by plasma membrane DAG signaling rather than ionic strength

by Benjamin König, Yuchen Hao, Sophia Schwartz, Andrew JR Plested, Tobias Stauber
Published 2019-06-01

A missense mutation accelerating the gating of the lysosomal Cl−/H+-exchanger ClC-7/Ostm1 causes osteopetrosis with gingival hamartomas in cattle

by Arnaud Sartelet, Tobias Stauber, Wouter Coppieters, Carmen F. Ludwig, Corinne Fasquelle, Tom Druet, Zhiyan Zhang, Naima Ahariz, Nadine Cambisano, Thomas J. Jentsch, Carole Charlier
Published 2014-01-01

In Vivo Evidence for Lysosome Depletion and Impaired Autophagic Clearance in Hereditary Spastic Paraplegia Type SPG11.

by Rita-Eva Varga, Mukhran Khundadze, Markus Damme, Sandor Nietzsche, Birgit Hoffmann, Tobias Stauber, Nicole Koch, J Christopher Hennings, Patricia Franzka, Antje K Huebner, Michael M Kessels, Christoph Biskup, Thomas J Jentsch, Britta Qualmann, Thomas Braulke, Ingo Kurth, Christian Beetz, Christian A Hübner
Published 2015-08-01

A mouse model for SPG48 reveals a block of autophagic flux upon disruption of adaptor protein complex five

by Mukhran Khundadze, Federico Ribaudo, Adeela Hussain, Jan Rosentreter, Sandor Nietzsche, Melanie Thelen, Dominic Winter, Birgit Hoffmann, Muhammad Awais Afzal, Tanja Hermann, Cecilia de Heus, Eva-Maria Piskor, Christian Kosan, Patricia Franzka, Lisa von Kleist, Tobias Stauber, Judith Klumperman, Markus Damme, Tassula Proikas-Cezanne, Christian A. Hübner
Published 2019-07-01